The Analysis Of The Relationship Between Risk Factors,TCM Constitution And TCM Syndrome Elements Of Restenosis After Percutaneous Coronary Intervention

Objective To explore the intervention risk factors,constituti on of TCM and distribution characteristics of syndrome elements of restenosis after PCI in patients with coronary heart diseas e.To explore the intrinsic relationship between syndrome elemen ts and the etiology and pathogenesis of restenosis after PCI in Chinese medicine.To analyze the correlation between restenosis after PCI and risk factors,constitution and syndrome elements of TCM.To provide theoretical basis for etiology and pathogene sis of restenosis after PCI in coronary heart disease.To provid e objective basis for preventing restenosis after PCI in terms of intervention risk factors,constitution of TCM and syndrome elements.Methods According to the principle of randomized control,pati ents admitted to Cardiology Department of Hubei Traditional Chi nese Medicine Hospital from November 2016 to August 2018 were s elected for PCI treatment of coronary heart disease,which met the inclusion criteria of this study,signed the informed conse nt form,and underwent coronary angiography reexamination 6-10 months after operation.Under the requirements of the unified standard,the clinical case report forms are used to collect info rmation.Clinical information of the subjects was collected by c ardiologists(Cardiovascular Internal Medicine)of Hubei Hospit al of Traditional Chinese Medicine and above,including general information(name,sex,age,place of origin,current residenc e,telephone number,etc.),past history,personal history,fam ily history,symptoms and signs,information of four diagnostic methods of traditional Chinese medicine,electrocardiogram,co lor Doppler echocardiography,coronary artery construction.Fil m materials,laboratory examinations,etc.At the same time,eac h participant in the study group collected "Diagnostic Scale of Coronary Heart Disease and Angina Pectoris Syndrome Elements" and "Self-Test Form of Constitution and Discrimination of Tradi tional Chinese Medicine",which were filled out by trained inve stigators after one inquiry.The above information was collecte d once at the time of admission and again at the time of corona ry angiography reexamination from June to October.The data of t his study are analyzed by SPSS 17.0 statistical software.The st atistical descriptions of the measurement data obeying or appro ximating normal distribution are made by `x±s,adopting t-test,the counting data uses Chi-square test and Pearson Chisquare te st.The correlation analysis between risk factors and TCM consti tution of transient ischemic attack and ischemic cerebral strok e adopt Logistic regression analysis of unconditional bicategor ized Data.All data analysis showed significant difference with P<0.05.Combined with clinical expertise,the statistical resul ts were analyzed.Results 1.In restenosis group,smoking history,diabetes mellitus,hypertension,dyslipidemia and high C-reactive protein acc ounted for a higher proportion;smoking history,diabetes melli tus,hypertension,dyslipidemia,high C-reactive protein and di sease occurrence had statistical difference(P < 0.05),overwei ght and drinking history had no significant difference in reste nosis group(P > 0.05).2.In restenosis group,the proportion of blood stasis,qi-d epression,Qi-deficiency and phlegm-dampness was higher,and th e proportion of blood stasis,qi-depression and phlegm-dampness was significantly higher than that of control group(P < 0.05).Because of the distribution of Qi-deficiency in coronary heart disease after PCI,both of them had more distribution of Qi-def iciency temperament,so Qideficiency temperament was found in r estenosis group and non-restenosis group.There was no statisti cal difference(P > 0.05).Blood stasis,qi depression and phle gm dampness were positively correlated with restenosis after PC I(P < 0.05),and there was no significant difference in the qu ality of peace between the two groups(P > 0.05).3.In restenosis group,the proportion of blood stasis,Qi d epression,Qi deficiency and phlegm-dampness was higher,and th e proportion of blood stasis,qi depression and phlegm dampness was significantly higher than that of control group(P<0.05).Qi deficiency was higher in both groups,but there was no statist ical difference between the two groups(P>0.05);blood stasis,Qi depression,phlegm and dampness were positively correlated w ith restenosis after PCI(P<0.05).Conclusion 1.Smoking history,diabetes mellitus,hypertension,dyslipidemia and high Creactive protein were higher in the restenosis group,which were positively correlated with the occurre nce of restenosis after PCI,and were the intervention risk fac tors for restenosis after PCI.2.Blood stasis,Qi depression and phlegm dampness are posit ively correlated with restenosis after PCI.It shows that the c onstitution of patients with restenosis after PCI is mainly blo od stasis,Qi depression and phlegm dampness.The proportion of Qi deficiency is higher in both groups.Although there is no s ignificant difference between the two groups,attention should be paid to it.3.Blood stasis,qi depression and phlegm dampness are posit ively correlated with restenosis after PCI,which indicates tha t the occurrence of restenosis after PCI is closely related to phlegm,blood stasis and Qi stagnation.Qi deficiency syndrome also accounts for a high proportion in restenosis group,which indicates that the essence of restenosis after PCI is still def iciency and deficiency,and restenosis patients are in acute st age,so the main clinical manifestation is standardization.4.In the process of prevention and treatment of restenosis afte r PCI,we can intervene in smoking,diabetes,hypertension,dys lipidemia,high Creactive protein and other risk factors.At th e same time,we can also regulate the constitution of patients,and make the blood stasis,qi depression and phlegmdampness qu ality as much as possible as possible distributed in normal peo ple.Finally,we can prevent and treat blood stasis from the pe rspective of TCM syndrome elements.In order to achieve the goa l of combining traditional Chinese and western medicine in the prevention and treatment of diseases,patients are treated withremoving blood stasis,removing dampness and resolving phlegmin patients with qi depression and expelling dampness andphlegmin patients with phlegm dampness.