A System Review On Clinical Effect Of Acupoint Injection For Trigeminal Neuralgia

Objective:Acupoint injection in the treatment of trigeminal neuralgia effect no conclusive evidence, the evaluation system proposed in circular medicine on acupoint injection for treatment of trigeminal neuralgia curative effect is evaluated.Methods:According to the system evaluation principle of Cochrane collaboration network, the retrieval strategy is formulated, and the RCTs or CCTs of the treatment of trigeminal neuralgia by acupuncture point injection at home and abroad is comprehensively retrieved. Computer search Tsinghua CNKI database. PubMed, CBM and other database. Making the inclusion criteria and exclusion criteria for literature screening. And then extract the data, and then according to the Cochrane collaboration network of "bias risk assessment standard" to screen out the quality rating of the literature. Using RevMan5.3 software to analyze the data of Meta, and using GradePro3.6 software to evaluate the quality grade of the final evidence.Results:At the end of the 10 studies, a total of 715 patients were included in the study. Seven Research Report (n=491) acupoint injection combined with acupuncture and acupuncture clinical total effective rate, the combined effect of the amount of RR=1.22,95%CI[1.13,1.30]. Seven studies, the research is with Chinese medicine acupoint injection, RR=1.22,95%CI[1.09,1.36]; three research is d)+local anesthetics acupoint injection, RR=1.19,95%CI[1.08,1.31]; one study is vitamin acupoint injection, meta analysis RR=1.33 95%CI[1.04,1.72] The effect of acupoint injection combined with acupuncture is better than that of simple acupuncture.2 research is the control point injection and oral administration of carbamazepine, RR=1.12,95%CI[0.94,1.33], the combined effect of the amount of CI crossing that two study combined the results were not statistically significant, can not explain the efficacy of point injection is better than carbamazepine.1 articles reported the acupuncture point injection combined with electroacupuncture and simple electroacupuncture, the difference between the two groups was statistically significant (P<0.05). The results indicate that the effect of acupoint injection combined with electroacupuncture is better than that of simple electroacupuncture. But its Meta analysis of 95%CI RR cross invalid line, can not be drawn acupuncture point injection combined with the efficacy of acupuncture is higher than the simple result of the affirmative. GRADE evidence quality evaluation, acupuncture point injection combined with acupuncture VS simple acupuncture, point injection of VS C Masi Bing quality grade are D level (low very).12 studies have not reported adverse reactions of acupoint injection therapy, and its safety is reliable.Conclusion:Point injection treatment of trigeminal neuralgia may have a certain effect, not reported adverse reactions. However, due to the low quality of literature, the number of the literature is less, the language is only Chinese, making the conclusions of the reliability of the impact, and the GRADE evidence quality rating is low, the results need to be treated with caution. Therefore, it is necessary to carry out high-quality clinical RCTs, to provide a more reliable clinical evidence for the treatment of trigeminal neuralgia. There are many kinds of drug selection in the treatment of TN by acupuncture point injection, which is not standard. More relevant studies are needed to standardize the drug selection for the treatment of TN by acupuncture point injection, and to provide a better drug injection solution.