The Effect Of Oral Care With Medication Ice On The Radioactive Oral Mucositis In Patients With Nasopharyngeal Carcinoma

Objective:To evaluate the special mouth rinse ice whether is helpful to reduce the incidence of oral mucositis.Methods: In March to August of 2016 in the first affiliated hospital of Zhengzhou university radiotherapy branch line of radiotherapy of the nasopharyngeal carcinoma patients in hospital. Radiation section of the new hospital of radiotherapy of nasopharyngeal carcinoma patients underwent screening, screening can into the group of patients, signed the informed consent. Patients randomly seal has random digital envelope, an odd number into the control group, even in the experimental groups. Patients treated with topical cryogenic nursing intervention, control group patients, the routine nursing was used in radiotherapy after evaluation, once a week to evaluate radiation again after the end of January, observe the incidence of radioactive oral mucositis and oral comfort, evaluation of local nursing intervention measures is effective in low temperature.Results: There was no statistically significant difference(gender, ages, radiotherapy times, radiotherapy dose, concurrent chemoradiotherapy, TNM stages) in experiment and control group. The incidence of oral mucositis of the experiment group was 44.9%(31/69), the incidence of oral mucositis of the control group was 76.8%(53/69). The incidence of oral mucositis in experiment group was significantly lower than the control group(x2 =14.618,P =0.000).The numbers of oral mucositis in experiment group: one grade 12 patients(17.4%), two grade 9 patients(13.0%), three grade 6 patients(8.7%), four grade 4 patients(5.8%), The numbers of oral mucositis in control group: one grade 17 patients(24.6%), two grade 11 patients(15.9%), three grade 17 patients(14.6%), four grade 8 patients(11.6%). There was statistically significant difference in two groups, x2=16.619,P=0.002.The numbers of dry mouth in experiment group: none symptom 21 patients(30.4%), mild symptom 25 patients(36.2%), moderate symptom 17 patients(24.6%), serious symptom 6 patients(8.7%). The numbers of dry mouth in control group: none symptom 6 patients(8.7%), mild symptom 15 patients(21.7%), moderate symptom 34 patients(49.3%), serious symptom 22 patients(31.9%). There was statistically significant difference in two groups, x2 =24.250, P =0.000.The numbers of pharyngalgia in experiment group: none and mild symptom 37 patients(53.6%), moderate symptom 22 patients(31.9%), serious symptom 10 patients(14.5%). The numbers of pharyngalgia in control group: none and mild symptom 7 patients(10.1%), moderate symptom 32 patients(46.4%), serious symptom 30 patients(43.5%). There was statistically significant difference in two groups, x2 =32.306, P =0.000.The numbers of taste alteration in experiment group: none symptom 17 patients(24.6%), mild symptom 30 patients(43.5%), moderate symptom 15 patients(21.7%), serious symptom 7 patients(10.1%). The numbers of taste alteration in control group: none symptom 5 patients(7.24%), mild symptom 20 patients(29.0%),moderate symptom 27 patients(39.1%), serious symptom 17 patients(24.6%). There was statistically significant difference in two groups, x2 =16.141, P =0.001.Conclusion: Mouth rinse ice can significantly reduce the incidence of radioactive oral mucositis, and can reduce the severity. And ice can improve the oral comfort, including dry mouth, pharyngalgia, and taste alteration.