Study On The Relation Between Deep Venous Thrombosis After Total Knee Arthroplasty And Diabetes Mellitus

[Objective] To analyze the relation between deep vein thrombosis formation after total knee arthroplasty (TKA) and diabetes through the clinical data, and provide reference for personalized prevention and treatment of deep vein thrombosis after TKA according to the conclusion.[Methods] In this study, we use the method of historical cohort study to implement the study. In this study, we selected patients who received unilateral artificial total knee arthroplasty to treat KOA in teaching hospital of Chengdu university of TCM and Sichuan Provincial Orthopaedics Hospital from March 2014 to 2015 December. All the patients were divided into diabetes group and control group according to the presence of diabetes. After TKA, all the patients were examined by colored Doppler ultrasonography to detect the occurence of lower extremity deep venous thrombosis after total knee arthroplasty. Compared to diabetes group and control group and diabetes for more than 10 years and a history of diabetes group group it is less than the incidence of DVT and related laboratory benchmark 10-year group whether there are differences, analysis of diabetes and its history and TKA postoperative deep venous thrombosis Relationship.[Result] According to the standard of the 264 patients,68 cases of diabetes group and 196 cases in the control group were selected.40 cases of lower extremity deep venous thrombosis occurred after TKA, occurrence rate of 15.2%, which in diabetic group occurred deep venous thrombosis of the lower extremity 19 cases, accounted for 27.9%of the total number of cases and the control group, the incidence of deep venous thrombosis of the lower limbs in 21 cases accounted for 10.7%of the total number of cases. By Logistic regression analysis, the risk of lower extremity deep venous thrombosis after total knee arthroplasty in diabetic group was 4.6 times that of non diabetic group (95%CI (6.212-1.183), P> 0.05.The risk of lower extremity deep venous thrombosis after total knee arthroplasty was 1.93 times more than ten years in patients with diabetes mellitus (95%CI 1.183 to 6.212), P> 0.05. The mean preoperative D-dimer of diabetes and control groups were 691.37 ± 327.61?g/L and 360.91 ± 190.39?g/L,the mean postoperative D-dimer of the two groups were 3638.65 ± 852.86?g/L and 2380.04 ± 690.49?g/L, both groups significant difference between postoperative and preoperative and comparison between the two groups before the same significant postoperative.There was no significant difference between the two groups in age, sex, hypertension, prevalence, body mass index (BMI), operation time, intraoperative bleeding volume, tourniquet time.[Conclusion] The incidence of postoperative lower extremity deep venous thrombosis among patients with diabetes is higher than those without diabetes after unilateral TKA. It is possible that the incidence of postoperative lower extremity deep venous thrombosis after total knee arthroplasty is associated with a history of diabetes positively.