Study On The Relationship Between Precocious Puberty And Children's Lifestyle And Family Factors

Objective:To realize the difference of the growth and development between precocious puberty and normal children,explore the relationship between precocious puberty and lifestyle as well as family factors,screen out the risk factors related to precocious puberty,propose measures and recommendations for preventing precocious puberty,which provides scientific basis for the prevention and treatment of precocious puberty in children.Methods:A case-control study was conducted among 126 newly diagnosed central precocious puberty children and 126 controlled children with age,sex mated from June 2015 to August 2016,who were chosen from maternal and child health care hospital in Jinhua and the pediatric department of Endocrinology Affiliated Hospital of Hangzhou Normal University.The evaluation of the growth and development status includes physical measurement,the second sex character,bone age,the basic value of sex hormones and the GnRH provocation test.Seven aspects including general information,child birth status and maternal status,diet,lifestyle,genetic factors,family economic condition,family environment and accompany of parents in childhood were assessed through questionnaire.Those factors are analyzed through SPSS20.0,T test,chi-square test,rank sum test and binary logistic regression.Results:(1)The average height,weight,BMI,bone age in the case group were all higher than ones in the control group,and the prevalence rate of obesity in case group(26.2%)was higher than that in control group(14.3%),the differences were statistically significant(p<0.05).(2)According to the results of univariate analysis,precocious puberty is associated with the factors such as BMI,obesity,siesta habits,exercise time,food intake,mother's menarche age,whether relatives have precocious puberty,father's education,parents' education and occupation,intimacy between children and father,how much time a child is without father and father's company.Binary logistic regression analysis shows that siesta(OR=3.135,p<0.001),food intake(OR=1.944,p=0.002)are positively correlated with precocious puberty;mother's education(OR=0.576,p=0.004),mother's menarche age(OR=0.645,p<0.001),father's company(OR=0.763,p=0.038)are negatively correlated with precocious puberty.Conclusions:(1)At the same baseline level,the growth and development of children in the case group were higher than ones in the control group.(2)Mother's early menarche age,large appetite,father's company shortage are the risk factors for precocious puberty,however,high level of mother's education,siesta habits are the protective factors.It should be done to strengthen health education,cultivate children's healthy dining habits and lifestyle,encourage parents to spend more time with their children and improve the health management services for children.