Clinical Observation Of SAA,hsCRP And PCT Interventional Therapy In Patients With Jia Wei Ma Xin Fu Zi Decoction To Acute Exacerbation Of Chronic Obstructive Pulmonary Disease(Lung-kidney-yang Deficiency Type)

Objective: To observe the clinical effects using Jia Wei Ma Xin Fu Zi Decoction that have the actions such as Wen Shen Bu Fei Zhi Ke Ping Chuan Hua Tan to treat the patients of the Fei Shen Yang Xu of Acute Exacerbation of Chronic Obstructive Pulmonary Disease,Further validating the efficacy of Modified Jia Wei Ma Xin Fu Zi Decoction in the treatment of AECOPD,thus demonstrating the advantages of traditional Chinese medicine in the treatment of acute diseases.Methods: In this study,72 cases of elective cases were selected as the selected subjects in the hospitalized department of cardiopulmonary department of yun nan Traditional Chinese Medicine Hospital,and the nature and purpose of the trial were informed and agreed by the subjects and their families.Routine medication,until the end of the trial,included in the observation of patients using randomized grouping method,were randomly divided into treatment group 36 cases and 36 cases of the control group.Treatment group in oxygen therapy,to maintain the balance of liquid and electrolyte,nutritional support of the basic treatment of addicted to Jia Wei Ma Xin Fu Zi Decoction + Doxofloxacin injection + injection of cefodizime sodium + injection with ambroxol hydrochloride treatment,the control group in oxygen therapy,Maintain Liquid and Electrolyte Balance,Nutritional Support for Basic Treatment to Doxofloxacin Injection + Injection for Cefodizime Sodium + Injection for Treatment with Ambroxol Hydrochloride.The treatment group and the control group were treated with continuous treatment: 15 days,15 days after the observation of the two groups of patients before and after treatment of comprehensive clinical efficacy,and the two groups of patients before and after treatment of the indicators were compared,with reference to "Chinese medicine clinical research And the SPSS19.0 statistical software was used to statistically evaluate the indexes of the two groups before and after treatment,and finally to evaluate the curative effect.Results: 72 cases were observed,36 cases in the treatment group and 36 cases in the control group.There was no significant difference in gender and age between the two groups before treatment(P> 0.05).The total effective rate was 88.8% in the statistical group,which was significantly different from that in the control group(77.8%)(P = 0.038 <0.05),which was statistically significant.Through the comparison of TCM syndromes,efficacy indexes and safety indexes of the two groups before and after treatment,the TCM syndrome scores,arterial blood gas analysis,inflammatory index,blood routine,pulmonary function,hospitalization time(Cough,sputum,wheezing,shortness of breath)and secondary symptoms(chills)were not found in the two groups after treatment(P> 0.05),no statistically significant and comparable(P <0.05),and there was significant difference between the two groups(P> 0.05).(2)Compared with the control group,the two groups of SAA and hs CRP treatment groups were significantly better than those in the control group(P <0.05),and the difference was significant(P <0.05),statistically significant;PCT treatment before and after no significant change,no significant difference(P> 0.05),no statistically significant,indicating that the choice of observation of AECOPD patients PCT no significant changes;(5)after treatment Compared with the control group,the WBC(109 / L)and NEUT(%)in the treatment group were significantly better than those in the control group(P <0.05).(6)Compared with the control group,(P <0.05),which was statistically significant.(7)Compared with the control group,there were significant differences(P <0.05)between the two groups after treatment,and the difference was statistically significant.(P <0.05).There was no significant difference between the two groups(P> 0.05).There was no significant difference between the two groups(P> 0.05).There was no significant difference between the two groups(P> 0.05)Observe safe and reliable.Conclusion: Through the study of this subject,the use of integrated traditional Chinese and Western medicine method is more effective than traditional western medicine to control the acute attack of chronic obstructive pulmonary disease,and concluded that:(1)In the treatment of antibiotics and hospitalization time,the treatment group was better than the control group;(P <0.05).Conclusion The results showed that there were no significant differences in the safety indexes such as respiratory rate,heart rate,blood pressure,liver function and renal function in patients with clinical symptoms,inflammatory parameters,blood routine,arterial blood gas and pulmonary function.Effectiveness of Traditional Chinese Medicine in Treating Acute Diseases.