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Effect Of Body Coposition Of Fat Mass And Lean Mass On Bone Mineral Density In Elderly People

Posted on:2018-01-06Degree:MasterType:Thesis
Country:ChinaCandidate:S ChenFull Text:PDF
GTID:2334330518952706Subject:Endocrine
Abstract/Summary:PDF Full Text Request
Objective: To investigate the impact of body composition of fat mass(FM)and lean mass(LM)on bone mineral density(BMD),and the relationship between sarcopenia and osteoporosis.Methods: 32 men and 49 women from The First Affiliated Hospital of Guangxi Medical University were enrolled in this study.Height,weight,body mass index(BMI)off all the subjects were measured,and BMD,FM and LM were measured by dual-energy X-ray absorptiometry(DXA).Skeletal muscle index(SMI)was described as appendicular skeletal muscle mass divided by height square(ASM/height2).Pearson's correlation analysis and Multiple regression analysis were used.Results: Men have higher percentage of lean mass than women,while women have a higher fat mass than men.The prevalence of sarcopenia in women(16.3%)is lower than that of men(46.9%)in this study.BMD is positive correlation with regional LM and FM in men(Lumbar : LM r = 0.577 P = 0.001,FM r = 0.465 P = 0.007;Femur: LM r = 0.360 P = 0.043;Hip: LM r = 0.452 P = 0.009)as well as in women(Femur: LM r = 0.337 P = 0.018;Hip: LM r = 0.292 P = 0.042).Besides,SMI has positive correlation with SMI in both genders(male: r = 0.575 P = 0.001;female: r = 0.074 P = 0.000).Conclusions: For both men and women,regional BMD is significantly associated with lean mass,SMI shows significant positive correlation with BMI.But the prevalence of sarcopenia and has gender differences.The lower BMI populations should pay attention to sarcopenia early,especially for men and elderly woman.
Keywords/Search Tags:skeletal muscle index, bone mineral density, sarcopenia, osteoporosis
PDF Full Text Request
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