Correlation Between Platelet/Lymphocyte Count Ratio And Ischemic Cerebrovascular Disease

Objective: To investigate the correlation between Platelet/lymphocyte(PLR)and ischemic cerebrovascular disease(ICVD).Methods: We selected 307 cases patients of ICVD in our hospital from January 2015 to January 2016.Among them,cerebral infarction 263 cases,transient ischemic attack(TIA)44 cases.selecting 307 healthy cases of the corresponding period as control group.Recording age,gender,history of smoking,history of drinking of two groups,and recording the lymphocyte count,platelet count,calculating the platelet/lymphocyte count ratio(PLR)value.We compared PLR value of two groups,and analyses the correlation between PLR and ICVD carotid atherosclerosis by using logistic regression analysis.Results: The PLR value of the ICVD group was higher than of the control group,the difference was statistically significant(P<0.05).The PLR value in both male and female were higher in the ICVD group than that of male and female in the control group.The PLR value in both cerebral infarction was higher than that of the control group,the difference was statistically significant(P<0.05).307 cases ICVD patients,68 cases carotid IMT were normal,48 cases carotid IMT were thickening,191 cases plaque formation,among them,the PLR value in the plaque formation group was significantly higher than both thickening IMT and the normal IMT group,the difference was statistically significant(P<0.05).Multivariate logistic regression analysis showed that the increased PLR value was an independent risk factor for carotid atherosclerosis plaque formation(OR=1.012,95%CI 1.001-1.024).Conclusion: The PLR value is an important risk factor of ICVD.The PLR value is closely related to the formation and development of carotid atherosclerosis plaque formation in patients with ICVD,can reflect the degree of carotid atherosclerosis.