Study On The Regularity Of Traditional Chinese Medicine Syndromes Pre- And Post-menstruation In Hy Perplasia Of Mammary Gland

Object:In this paper,through the use of cluster analysis and principal component analysis of breast hyperplasia patients Pre-and Post-menstruation period of the distribution of TCM syndromes and the syndrome type of primary and secondary disease,and then the disease "Chinese medicine cycle therapy" to develop the feasibility of treatment principles,To provide a reference for syndrome differentiation and treatment of breast hyperplasia.Methods:A total of 193 patients with breast hyperplasia diagnosed by the Department of Breast Surgery at the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2015 to January 2017 were enrolled.All patients' names,sex,age,time of investigation,address,Education,career,marriage,past history,family history,menstrual history,fertility history,symptoms,tongue moss pulse,signs and other information.SPSS20.0 statistical software was used to analyze the symptoms and tongue moss pulse frequency,remove the <10% of the variables,select ? 10% of the variables for cluster analysis,summed up the breast hyperplasia patients before and after menstrual period of TCM syndrome.And by two deputy chief physician titles above the clinical experts,combined with traditional Chinese medicine to determine the name of syndromes.The principal component analysis of the symptoms of each syndrome,each syndromes can be extracted from the main components.According to the results of clustering and the results of principal component analysis,the patients with breast hyperplasia were analyzed before and after menstruation,and the distribution of each syndrome was analyzed.Results:1.Frequencyof four frequency information analysis showed that:breast hyperplasia patients with premenstrual frequency ? 10% of the symptoms of a total of 48,Respectively,for the expansion or pain,depression,irritability,mouth bitter,mouth pale,mouth sticky,chest tightness,good too much interest,oropharyngeal dry,five upset hot,pantothenic acid,abdominal distension,Yaoxisuanruan,belching hiccup,Tinnitus,aphrodisiac cold,dizzy,tired body fatigue,Shenpi lazy words,insomnia and more dreams,hot hot night sweats,throat like plumage,loose stools thin,dry stool,stool bad mood,urine yellow,urine long,Nocturia,pale complexion,menstrual color,dysmenorrhea,menstrual quality,pale tongue,pale tongue,dark purple tongue,red tongue,dark red tongue,tongue side of the stasis,Thin white fur,white fur,little tongue coating,greasy tongue coating,pulse string,pulse thin,slippery pulse,pulse astringent;menstrual period after the frequency of ? 10% of thesymptoms of a total of 40,Were: chest pain or swelling,pain,breast pain,irritability,irritability,mouth bitter,mouth sticky,chest tightness,good too much interest,dry mouth,dry,pantothenic acid,abdominal distension,waistache soft,belching hiccup,Tinnitus,aphrodisiac cold,dizzy,tired body fatigue,Shenpi lazy words,insomnia and more dreams,hot hot night sweats,throat like plumage,loose stools thin,dry stool,urine yellow,urine long,nocturnal Long,pale complexion,pale tongue,pale tongue,pink tongue,thin white tongue,white tongue,little tongue coating,greasy tongue coating,pulse string,pulse sink,pulse thin,pulse astringent.2.Cluster analysis results: 193 cases of breast hyperplasia patients with four diagnostic information through the cluster analysis of menstrual period before the poly group for the four categories,namely: liver stagnation syndrome,spleen deficiency wet syndrome,Yin deficiency syndrome,kidney yang deficiency Failure of the month;menstrual period after the three categories,namely: liver and spleen deficiency syndrome,red any loss card,Yin deficiency heat syndrome.3.The main component of the results:menstrual period before the liver and phlegm coagulation syndrome main ingredient 1:chest failure for swelling or pain,chest tightness,the main component 2:depression,the main ingredient 3:throat like plumage.Spleen dampness Sheng Zheng main ingredient: mouth sticky,pantothenic acid,abdominal distension,pale complexion.Yin deficiency heat Sheng Zheng main ingredient 1:oropharyngeal dry,hot flashes night sweats,dry stool,urine yellow,less tongue coating,the main component of 2:five upset hot.Kidney deficiency deficiency syndrome main ingredient 1:tinnitus,Shenpi lazy words,nocturia frequency,the main component 2:Yaoxisuanruan.Menstrual period after the liver and spleen deficiency syndrome main ingredient 1:pantothenic acid,abdominal distension,nocturia frequency,the main component 2:depression,throat,like plumage,the main component of 3: chest tightness.The main ingredient 1 is:Yaoxisuanruan,Shenpi lazy words,the main component of 2:tinnitus,the main component of 3:breast pain.Yin deficiency heat Zheng Zheng Ingredients 1:irritability,dry mouth,five upset hot,dry stool,urine yellow,less tongue coating,the main component 2:pulse sink.4 cases of breast hyperplasia before and after the menstrual period of the distribution of syndromes: 193 patients according to cluster analysis and principal component analysis of the results of dialectical,the results showed: menstrual period before the liver stagnation syndrome patients up to 78 cases(40.4%(23.8%),35cases(18.1%)of Yin deficiency syndrome,34 cases(17.6%)of renal deficiency and deficiency syndrome,and 97 cases of menstrual period(50.3%),followed by yin deficiency syndrome in 53 cases(27.5%),liver depression and spleen deficiency in43 cases(22.3%).Conclusion:1.Mammary gland hyperplasia patients before and after menstrual symptoms can be different,which can be classified into different syndromes.2.The results of cluster analysis can extract the main components of each syndrome,and provide objective basis for clinical syndrome differentiation.3.According to the manifestation and recurrence of different syndromes in patients with hyperplasia of mammary gland,modern Chinese medicine can be used on the basis of syndrome differentiation and treatment,Blood and blood.4.I believe that the application of clinical investigation combined with multiple statistical analysis,can be used in the current norms and standards for mathematical verification,you can establish a more scientific,consistent with the clinical practice of TCM syndrome differentiation model.