Clinical Observation Of Shenmai Qi Lianyin In Treating Primary Type 2 Diabetes Millitus With The Syndrome Of Qi-yin Deficiency And Dampness-heat

Objective:To observe the clinical effect of Shenmai Qi Lianyin in the treatment of primary type 2 diabetes mellitus with the Syndrome of Qi-yin Deficiency and Dampness-heat,and to provide new ideas and clinical basis for the combination of traditional Chinese medicine and western medicine in lowering blood sugar and improving clinical symptoms.Methods:The subjects of this study were from December 2016 to December 2017 in the outpatient clinic of Department of Endocrinology,Yunnan traditional Chinese medicine hospital,which had 80 cases of type 2 diabetes mellitus(the Syndrome of Qi-yin Deficiency and Dampness-heat).Randomly divided into control group(Basic therapy + Metformin Hydrochloride Tablets)with 40 Cases,treatment group(Basic therapy + Shenmai Qi Lian Yin + Metformin Hydrochloride Tablets)of 40 Patients were treated for 8 weeks,with fasting plasma glucose(FPG),Two hours postprandial blood glucose(2h PBG),Glycosylated hemoglobin(Hb A1c),Fructosamine(FRA),Body mass index(BMI),Insulin resistance index(HOMA-IR),Total cholesterol(TC),Triglyceride(TG),High-density lipoprotein cholesterol(HDL-C),Low-density lipoprotein cholesterol(LDL-C)and TCM symptoms as observation indicators.through statistical analysis,the changes of the two groups of indicators before and after treatment were observed.Results:1.During the course of treatment,5 patients dropped off because the loss of connection or failure to return to medical treatment.There were 37 cases in the control group and 38 cases in the treatment group after the experiment.2.The treatment group showed significant improvement in FPG,2h PBG,Hb A1 c,FRA,HOMA-IR,TC,TG,HDL-C,LDL-C,the difference was statistically significant compared with the control group(P<0.05).But there is no significant difference in BMI(P>0.05).It is suggested that the therapeutic effect of the treatment group and the control group on improving the body mass index of the patients is equal.3.The single score and total integral of TCM Syndrome could be improved effectively in treatment group,with significant statistical difference compared with the control group(P<0.01).4.The total effective rate of the treatment group was 84.21%,and the total effective rate of the control group was 62.16%,the difference was statistically significant compared with the control group(P<0.05).5.There was no side effects discovered in both groups during the treatment.Conclusion:Shenmai Qi Lian Yin can effectively improve the clinical indexes,such as blood sugar,blood lipid,body mass index,insulin resistance and so on,in the patients with Qi and Yin deficiency and dampness heat type 2 diabetes mellitus.At the same time,it has significant advantage in improving the symptoms of TCM.And there is no obvious adverse reaction after taking medicine,which lays a theoretical and practical foundation for further research and exploration in the future,and it is worthy of clinical promotion.