Shengban Mixture Treatment Of Immune Thrombocytopenia Primary Curative Effcet Observation

Objective:To explore the curative effect of self-made Chinese herbal preparation Shengban mixture combined with adrenocortical hormone in the treatment of chronic adult immune thrombocytopenia primary,and to popularize the application of Shengban mixture in clinical treatment of CITP,so as to provide a good treatment scheme for CITP patients.Methods: 60 adult patients with primary immune thrombocytopenia who were hospitalized in our blood oncology department from 2016 to 2017 were collected and divided into 30 cases of hormone group(Standard dose of adrenocorticosteroid,30 cases of combined group(Standard dose of adrenocorticosteroid + Shengban mixture),according to the order of admission treatment.15 days for one cycle,observe 2 cycles and followed up for 2 months.The clinical efficacy of western medicine,clinical symptoms of TCM,peripheral platelet count,long-term efficacy of patients before and after the treatment were analyzed.Results: there were 30 patients in the hormone group and 30 patients in the combined group.(1)Peripheral platelet count: after 15 days of treatment,the increase of platelet count in lift-slab mixture group was not significantly different from that in irritated hormone group.(P>0.05)After 1 month of treatment,the combination group was superior to the hormone group in increasing platelets.(P < 0.05);(2)Clinical efficacy of Western Medicine: no significant difference between the combined group and the hormone group in the clinical efficacy of Western medicine after 15 days.(P>0.05).After one month of treatment,the combined group was superior to the hormone group.(P < 0.05);(3)Clinical symptom score of TCM:no significant difference between the combination group and the hormone group in TCM syndromes score after the first course of treatment.(P>0.05)(4)After two courses of treatment,the combination group is superior to the hormone group in TCM symptom score.(P < 0.05).Conclusion:Shengban mixture has better effect in the treatment of chronic adult immune thrombocytopenia primary,compared with the use of hormone alone in the increase of peripheral platelet count,relief of clinical symptoms.In the maintenance treatment stage of hormone reduction,Shengban mixture can effectively maintain platelet stability,which is worthy of further promotion in clinical practice.