| Y Medicines Co since its inception, has certain social awareness and market coverage. However, in recent years, with the increasing expansion of the scale of the enterprise and employee, gradually exposed some problems, particularly sales problems, has seriously hindered the further development of the company. In order to solve the problems, we must proceed from the actual situation of the company, proposes the solution to the problems, and gradually perfect the incentive system, optimization of sales staff, and thus the stability of the sales team, motivate sales personnel working enthusiasm, for the better development of enterprises human resources lay a good foundation.In this paper, by using the method of literature research and case study combined. This paper firstly summarizes the need motivation theory, briefly summarizes the research status about the motivation of the sales personnel, analyzes the common problems of sales staff characteristics and pharmaceutical enterprise human resources management, as the theoretical support of this study. Then, combined with the Y Medicines Co of the current internal and external environment, current situation of the company sales staff incentive analysis, through the employee satisfaction survey, interviews, dig out the company has in the performance appraisal, salary and welfare, staff training and other aspects of the problem, for the problems to analyze, find out the reason. Finally, the existing incentive mechanism of Y Medicines Co was optimized, and according to the characteristics of the industry and enterprise situation, proposed should also strengthen the moral incentive and incentive mode of vision. At the same time, pay attention to and strengthen dynamic management of the leader’s incentive system, implement differential incentive, improve the quality of sales personnel, the establishment of people-oriented corporate culture and other factors, can be used to improve the incentive system.Through the Y Medicines Co sales staff incentive study and operation optimization of system, can promote the sales staff to work better, improve the work performance. Finally for the development of power enterprises. |