Analysis Of Risk Factors For Death In Non-small Cell Lung Cancer And Treatment Of Traditional Chinese Medicine

Purpose: Inquire the risk factors of death of in non-small-cell lung cancer(NSCLC)and directive death reasons,provide the basis for scientific,reasonable treatment plan.Method: We choose 51 patients who are died of NSCLC in the affiliated hospital of Liaoning University of TCM of oncology department from 2014 year in May to 2016 may then summary and analysis their gender,age,Karnofsky,performance,status,smoking history,history of previous lung diseases,clinical stage,patho-type,with or without pleural fluid and operation,with or without the application of Traditional Chinese Medicine,the number of application of Traditional Chinese Medicine,the application of chinese patent medicine,testing patients hemoglobin and blood platelet levels at last admissiom.Traditional Chinese medicine symption score.Results:1.In 51 cases of NSCLC the overall median survival time was 15 months and the1,2,3 year accumulative survival rates were 60.8%,33.3%,25.5%.2.The univariate analysis of death risk factors with NSCLC :clinical tumor stages.Karnofsky performance status,smoking history,With or without pleural fluid,weather the operation,with or without the application of TCM,the number of application of Traditional Chinese Medicine,blood platelet levels,hemoglobin levels,Scores of TCM symptoms were the risk factors of death in patients who are diagnosed as NSCLC,all P<0.05.While their gender,age,history of previous lung diseases,patho-type,the application of chinese patent medicine are not prognosis factors.3.Multivariate analysis of death risk factors with NSCLC: Clinical tumor stage.Karnofsky performance status,With or without pleural fluid,the number of application of Traditional Chinese Medicine,,Scores of TCM symptoms were independent death risk factors to patients with NSCLC,all P<0.05.Relative risk are 1.595,0.951,0.372,0.267,2.186.Others do not show the prognosis value of independence to survival rates.4.The directive death reasons: 28 cases of respiratory failure patients(54.90%),their median survival time was 6 days;9 cases of General failure patients(17.65%),their median survival time was 50 days;8 cases of pulmonary encephalopathy patients(15.69%),their median survival time was 11 days;6 cases were other cause(including 1 case of myocardial infarction patient,4 cases of brain metastasis patients,1 case of congestive heart failure patient)Conclusion:1.Clinical tumor stage,Karnofsky performance status,With or without pleural fluid,the number of application of Traditional Chinese Medicine,Scores of TCM symptoms were independent death risk factors to patients with NSCLC.smoking history,weather the operation,weather the application of Traditional Chinese Medicine,blood platelet levels,hemoglobin levels are not independent prognosis factors,though they show prognosis value to survival rates.we take Active actions to the risk factors to the death of patients with NSCLC,and adopt a more reasonable,individualized treatments to reduce risk of death,improve prognosis and prolong the survival time.blood platelet levels,hemoglobin levels,Scores of TCM symptoms provide a reference for pre-deathbed mortality and clinical management.2.The rational long-term application of TCM can improve the prognosis and prolong the living period.3.Respiratory failure,General failure,pulmonary encephalopathy are main reasons for death.