The Study On The Properties Of Metalloporphyrin Derivatives

Porphyrins and metal porphyrin derivatives,such as chlorophyll,heme and cytochrome,exist ubiquitously in plants and animals organisms and the nature.Due to their unique structures and miscellaneous properties,porphyrins and metal porphyrin derivatives have been greatly applied in multidisciplinary fields including analytical chemistry,synthetic chemistry,material chemistry,biochemistry and medical science.As one of the metal porphyrin derivatives,sodium copper chlorophyll plays a decisive role in the photosynthesis of plants and the life of human.Heme is an important porphyrin complex with iron,also a kind of biological iron products,which is non-toxic or of zero side effects.On basis of studies on UV-visible and FT-IR spectra of sodium copper chlorophyll and heme,this thesis mainly reports the following researches:(1)The chlorophyll was extracted from fresh spinach leaves by the traditional solvent leaching method,along with drying,grinding,leaching and other procedures.The resulting mixture was saponificated,purificated,substituted with copper and added sodium hydroxide,then afforded the final products sodium copper chlorophyll.The chlorophyll and sodium copper chlorophyll were characterized using Artar370 model FT-IR and TU810-PC model UV-Vis.Our experimental results are in good agreement with the result of reference.(2)Several colloids of silver iodide,silver bromide and ferric hydroxide,and their complexes with sodium copper chlorophyll and hemin solution were prepared.The spectral properties of these complexes,in particular the changes of Soret bands and Q bands,were mainly determined.The experiments evidenced that different colloidal species and different charging situation of a same species showed different influences on electronic absorption of these two kinds of metalloporphyrin derivatives.(3)Electronic structures and spectral properties of porphyrins and their derivatives were investigated through the density functional theory(DFT).At first the factors that affect the PC calculation time,were discussed.Then the structures of protoporphyrin and tetraphenylporphyrin zinc complexes were fully optimized using the density functional theory in the selected 6-31G(d,p)basis set.In addition,the UV-visible absorption spectra of protoporphyrin and tetraphenylporphyrin zinc complex were studied by time-dependent density functional theory.The calculation results are relatively significant in paths to the further deep understanding of the electronic structures and spectral properties of porphyrins and their derivatives.