| The number of patients with nerve injury has increased rapidly due to the development of society and rising proportion of aging population.Clinical observation shows that most of the patients with nerve injury suffer from loss of perception and the movement disorder.Because of the situation,patients need to be assisted by external equipment to improve their ability to live independently.Tactile perception simulation and movement function reconstruction can be achieved by applying electrical stimulation with different parameters to such patients.Compared with the rehabilitation equipment like exoskeleton robot,the electrical stimulation system has the advantages of portability,simple operation and low energy consumption.At present,the penetration rate of electrical stimulation equipment in our community and family is not high and the participation of patients in the process of use is low.Therefore,the main task of this project is to design a multi-channel electrical stimulator and conduct research on effect evaluation and parameter setting based on it.(1)Principle of electrical stimulation and simulation of neuron modeling:Firstly,the formation process and propagation mechanism of action potential are analyzed from the perspective of electrostimulation physiology.Secondly,the principles of electrical tactile perception and functional electrical stimulation are explained from the neurobiological perspective.Thirdly,the Hodgkin-Huxley(H-H)equation is analyzed on the ion and mathematics levels.Finally,the H-H model is numerically simulated by MATLAB software.By changing different stimulation parameters,the operating mechanism and characteristics of nerve cells under those parameters are studied.(2)Design of multi-channel electrical stimulator:Firstly,the overall scheme of electrical stimulation is proposed based on the theory of human resistance model,human current effect and stimulation waveform.Secondly,the core parts of hardware design are introduced respectively:boost module,full bridge control module,detection module,protection module and the core parts of software design:function design,communication protocol design,human-machine interaction design.Finally,the parameter characteristics of the electric stimulator are verified by parameter test and human trial.(3)The electrical stimulation comprehensive effect evaluation model combining subjective and objective factors:Firstly,psychological grading experiment are conducted by changing different stimulation parameters,and the importance sequence of each parameter is preliminarily obtained through statistical results;Secondly,based on the AHP theory,weight analysis is carried out on the influencing factors of the effect of local electrical stimulation.Finally,the comprehensive effect evaluation model of electrical stimulation is established in view of subjective feelings of the experimenters.(4)Applied experimental research on electrical stimulation and model verification:Firstly,the experiment is carried out from three parts,including tactile perception reconstruction experiment,movement reconstruction experiment and evaluation model rationality verification experiment with the angle of finger joint.Secondly,each experiment is introduced from the aspects of experimental system construction,experimental process,experimental results and data analysis.Finally,the collected data are analyzed.The feasibility of the application of electrical stimulation is verified in the first two experiments and the application effect of various parameters is analyzed.The comparison between theoretical calculation and data measurement in the model validation experiment also verifies the rationality of the model to some extent. |
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