Effects Of Dietary Calcium-phosphorus Ratio And Vitamin D₃ Supplementation On Blood And Urine Physiochemical Indexes And Urolithiasis Occurrence In Hoggets Of Liaoning Cashmere Goats

The objective of this experiment is to explore the effect of the calcium-phosphorous ratio（Ca/P）and vitamin D₃ on the performance,physiochemical indexes of the blood and urine as well as urolithiasis incidence in hoggets of Liaoning cashmere goats.The first experiment.The calcium-phosphorus ratio of the diet was designed to be at a level of 2:1,1.5:1,and 1:1.The second experiment,design dietary calcium-phosphorus ratio of 1:1 and dietary calcium-phosphorus ratio 1:1 addition of vitamin D_3.During the experiment,the feeding conditions are nearly same among all groups and the goats could drink water and feed at will.The blood and urine samples of the were collected from test goats with limosis in the morning of the 0^th,20^th,40^th,60^th and 80^th days in order to test the content of Ca,P,creatinine,urea nitrogen and uric acid and observe the incidence of the experiment goats.The results are as follows.The first experiment.When the Ca/P was 1:1,the incidence in hoggets of Liaoning Cashmere Goats were 37.5%.The content of P,creatinine,urea nitrogen and uric acid in blood significantly increased（P<0.05）while the change of Ca content was not significant.Change of pH was not significant（P>0.05）.The Ca content decreased at first,then,increased despite no significant change（P>0.05）.The P content increased significantly（P<0.05）and the creatinine,urea nitrogen and uric acid also tended to increase,which indicated the 1:1Ca/P diets could increase the serum P succeeded by increasing urine P which could precipitate from the saturated urine and cause the urolithiasis.Due to the long-term bladder uroschesis,the renal function would suffer from the resulting toxins.The second experiment.The effect of the vitamin D₃ on the blood,urine and urolithiasis incidence in hoggets of Liaoning Cashmere Goats indicated vitamin D₃ supplement did not significantly affect the performance of the Liaoning Cashmere goats（P>0.05）.The Ca content of the blood increased significantly（P<0.05）while the content of the P and alkaline phosphatase are tended to decrease despite no significant difference（P>0.05）.Simultaneously,the vitamin D₃ supplement also kept the content of creatinine,urea nitrogen and uric acid of the serum and urine varying in the normal physiological range which could decrease the urolithiasis incidence in hoggets of Liaoning cashmere goats.To sum up,When the ratio of dietary calcium to phosphorus was 1:1,high phosphorus diets could cause significant increase in serum and urine phosphorus content in hoggets Liaoning cashmere.After 60 days of testing,serum creatinine,urea nitrogen,and uric acid levels in the experiment goats were significantly higher than those in the physiological range,indicating that the kidneys of the experiment goats were severely damaged,and glomerular filtration was decreased.The incidence of urolithiasis in the experiment goats was significantly increased.At the same time,feeding diets with a ratio of calcium to phosphorus of 2:1 to 1.5:1 is beneficial to preventing the occurrence of urolithiasis in hoggets Liaoning cashmere goats.2000 IU/kg vitamin D₃ supplement in diets of Ca/P 1:1 could increase serum Ca content of the Liaoning cashmere goats and decrease the incidence of urolithiasis.