The Clinical Research On The Clinical Efficacy Of Kidney Deficiency Infertile Women With Polycystic Ovary Syndrome Through The Method Of Xia Guicheng's Bushen Tiaozhou

Objective:It provides an effective TCM treatment program for patients with PCOS infertility by observing the clinical curative effect in the treatment of kidney insufficiency PCOS infertility patients with BuShen TiaoZhou method,and further evaluates the clinical efficacy of BuShen TiaoZhou method,which also provides the basis for further inheriting and carrying forward the academic thoughts and clinical experience of Professor Xia Guicheng,a master of Chinese medicine.Methods:The study chooses 60 patients who were diagnosed with PCOS infertility of kidney deficiency and randomly divides them into two groups of 30 cases.The trial group were treated with BuShen TiaoZhou method.And the control group were treated with letrozole(LE)for ovulation induction,and 2 courses of treatment were observed,which is 6 months.It evaluates the curative effect of BuShen TiaoZhou method by observing the general condition,basal body temperature(BB T),menstrual cycle,Kaohsiung clinical manifestation,laboratory related index,gynecological ultrasound and other changes in two groups before and after each course of treatment,and compareing the pregnancy rate and early abortion rate in the two groups.All the data are processed by SPSS21.0 statistical analysis software.The main methods used are t test,Mann-Whitney U test,?2 test and so on.Results:There was no statistical difference in terms of age,BMI,BBT,menstrual history,family history,infertility,Kaohsiung clinical manifestations,PCOM and laboratory related indicators between the two groups before treatment.The two groups are comparable.Comparison of total clinical efficacy:The total effective rates of the experimental group and the control group were 86.7%and 83.3%,and the pregnancy rates were 40%and 33.3%respectively.After statistical tests,the total effective rate and pregnancy rate of the experimental group were higher,but the difference between the two groups was not statistically significant(P>0.05).The two groups of pregnant women had a total of 22 people.Among the 22 groups the treatment course was relatively longer(P<0.05),but the early abortion rate was significantly lower than that in the control group(P<0.05).Body mass index(BMI)comparison:The overall BMI decreased in two groups before and after each course of treatment,the differences were statistically significant(P<0.05);between the two groups after treatment,P=0.017,suggesting that the experimental group was more effective in reducing weight loss compared with the control group.The basal body temperature(BBT)comparison:BBT biphasic rate was significantly higher in both groups before and after treatment,the differences were statistically significant(P<0.05);between the two groups after treatment,P=0.488,the difference was not statistically significant,indicating that the two groups were equally effective in the improvement of biphasic BBT.Comparison of menstrual cycle:The two groups were significantly shorter in menstrual cycle compared with before and after treatment(P<0.05).Compared between the two groups after treatment,P=0.020,showed that the trial group had better effect in improving menstruation,and the difference between the two groups was statistically significant.Comparison of clinical manifestations of Kaohsiung:Comparison of the two groups before and after treatment,the number of clinical manifestations in Kaohsiung were significantly reduced(P<0.05);between the two groups after treatment,P=0.045,the difference was statistically significant.It indicates that the trial group in improving the clinical manifestations of Kaohsiung is more effective.PCOM comparison:Compared with the two groups before and after treatment,the number of B-ultrasound showed PCOM were significantly decreased(P<0.05).There was no significant difference between the two groups after treatment,P=0.754 showed that the two groups had the similar efficacy in improving PCOM.Comparison of Laboratory-related:Compared with the two groups before and after treatment,AMH,T,FAI index,LH/FSH and HOMA-IR and other laboratory-related indicators were significantly improved,(P<0.05).After treatment,the treatment group was significantly better than the control group in improving AMH and HOMA-IR,and the difference was statistically significant(P<0.05),but in the T,FAI and LH/FSH aspects,the trial group is more effective.However,there was no significant difference between the two groups(P>0.05).Safety observation:Two groups of patients did not find abnormal liver and kidney function and other obvious adverse reactions during the test.Conclusion:The study found that the method of BuShen TiaoZhou is equivalent to the ovulation induction of LE in terms of total effective rate and pregnancy rate.Although the treatment course is relatively long,the advantage of the BuShen TiaoZhou method is that it can effectively reduce the early miscarriage rate of the patient,to ameliorate the physical and mental harm caused by miscarriage,help patients to lose weight,increase their confidence in overcoming the disease,significantly improve menstrual status and other endocrine disorders in patients,and have good safety,no obvious toxic and side effects.It can be further promoted in the clinical.