Clinical Efficacy Of Yiqijianpi Decoction In The Treatment Of Type 2 Diabetes Mellitus(Deficiency Of Spleen Deficiency Type)

Objective:To evaluate the efficacy and safety of Yiqi Jianpi Decoction in the treatment of type 2 diabetes mellitus(spleen qi deficiency type)through this study,and provide an objective clinical basis for TCM treatment of the disease.Methods:64 patients with spleen qi deficiency type 2 diabetes were randomly divided into the control group and the treatment group,with 32 cases in each group.On the basis of diet exercise treatment,patients were treated with metformin(0.5g/times,3 times daily)in the control group.The treatment group,treated with metformin as well,were treated together with Yiqi Jianpi Decoction(1 agent in the morning and evening).The treatment course lasted 12 weeks,and the changes of fasting blood glucose and postprandial 2H blood sugar,TCM syndrome and glycosylated hemoglobin in the two groups were observed before and after the treatment.Results:1.The contrast of fasting blood glucose and postprandial blood glucose 2 hours in two groups:after checking fasting blood glucose and postprandial blood glucose 2 hours,the results showed that fasting blood glucose and postprandial blood glucose 2 hours(FPG/2hPG)(P<0.05)were reduced in both treatment group and control group.Both treatments worked;Compared with the control group which only treated with metformin,the treatment group treated with both metformin and Yiqi Jianpi Decoction works better,P<0.05,where there was a statistical significant difference.The treatment group in improving FPG,2hPG was significantly better than the control group2.The contrast of the total score of patients with TCM syndrome in two groups:by comparing the total score(P<0.05)of TCM syndrome of patients in both groups,the results showed that both treatments can reduce the TCM syndrome total score(P<0.05).Compared with the control group whichonly treated with metformin,the statistics of the treatment group treated with both metformin and Yiqi Jianpi Decoction has a difference with statistically significance,P<0.05,compared with the control group,the treatment group can significantly improve the clinical symptoms of patients with traditional Chinese medicine.3.The contrast of the two groups of patients with glycosylated hemoglobin value:the treatments in both the treatment group and the control group can reduce glycated hemoglobin values(P<0.05);Compared with the control group which treated with single drug metformin,the difference between both group differ litter,P>0.05.which was not statistically significant.Conclusion:1.Yiqi Jianpi Decoction can effectively reduce the fasting blood glucose and 2 hours postprandial blood glucose in patients with type 2 diabetes mellitus(deficiency of spleen deficiency type).2.Yiqi Jianpi Decoction can significantly improve the symptoms of type 2 diabetes mellitus(spleen deficiency)patients with burnout fatigue,eating less but with abdominal distention,weakness,tastelessness,no appetite and other Chinese medicine clinical symptoms of Spleen Qi deficiency.3.Yiqi Jianpi Decoction is safe in the treatment of type 2 diabetes mellitus(deficiency of spleen deficiency type).