Clinical Study Of The Protective And Therapeutic Effect Of Yiqi Yangyin Quyu Decoction On Patienents With Unstable Angina Pectoris Complicated With Type 2 Diabetes Mellitus

Objective:To observe the protective effect of Yiqi Yangyin Quyu Decoction on patients with unstable angina pectoris complicated with type 2 diabetes mellitus, and explore the prevention and cure machenism of it on coronary heart disease(CHD),diabetes mellitus (DM)and their syndrome.Methods:40 cases of patients with unstable angina pectoris complicated with type 2 diabetes mellitus were randomly divided into two groups:A group(control group), twenty patients were dealt with conventional treatment; B group (treatment group), twenty patients were treated with conventional medicine combined with Yiqi Yangyin Quyu Decoction. The clinical syndrome were observed and the fasting plasm glucose (FPG),2h postprandial blood glucose(2hPG),total cholesterol(TC), triglyceride(TG),high density lipoprotein cholesterol(HDL-C), low density lipoprotein cholesterol(LDL-C) were measured before and after 14-day′s treatment,.Results:The clinical syndrome efficiency and the total efficiency were different remarkably between the treatment group and the control group,while the former is higher(P<0.05). The TC and LDL-C decreased significantly in treatment group, and compared with the control group,the curative effect of the treatment group was much more prominent.Conclusion: Yiqi Yangyin Quyu Decoction can ameliorate the syndromes of patients, enhance clinical efficiency,regulate the chaos of lipid metaboly, its working mechanis m ay be related to preventing myocardial ischemia and platelet aggregation,adjusting the metabolic disorder of lipid and blood glucose.