Effect Of Dispelling Turbidity And Removing Blood Stasis Method Combined With Point Pressing On Abnormal Blood Lipid In CKD 3-4 Patients With Phlegm Turbidity And Blood Stasis Syndrome

Objective: to investigate the clinical effect of removing turbidity and removing blood stasis combined with acupoint method in treating chronic kidney disease with dyslipidemia in phase 3-4.Methods: a total of 60 non-dialysis patients with CKD 3-4 were included in the study.The patients came from outpatients or inpatients of Guangxi University of traditional Chinese Medicine.The eligible cases were randomly divided into the treatment group and the control group according to the 1:1 ratio.30 patients in each group were treated for 6 months.The control group was treated with conventional basic therapy,while the treatment group was treated by removing turbidity and removing blood stasis combined with acupoint point therapy.Before and after treatment,totalcholesterol(TC),triglyceride-triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),serum creatinine(CR),blood urea nitrogen(BUN),glomerular filtration rate(eGFR)and TCM score were observed.Results:(1)TC index: after treatment,the average TC in the treatment group was4.82±0.73,the average value of control group was5.25±0.63,The difference between the two groups was statistically significant(P<0.05).The curative effect of the treatment group was better than that of the control group.(2)TG index: after treatment,the average TG in the treatment group was1.57±0.39,the average value of control group was1.83±0.46,the difference between the two groups was statistically significant(P<0.05).The curative effect of the treatment group was better than that of the control group.(3)HDL-C index: after treatment,the average value of HDL-C in the treatment group was 1.55 + 0.43,and the average value of the control group was 1.34 + 0.35,the difference between the two groups was statistically significant(P<0.05),and the treatment group was superior to the control group.(4)LDL-C index: after treatment,the mean value of LDL-C was 2.89 ±1.15 in the treatment group and 3.20 ±1.12 in the control group,the difference between the two groups was statistically significant(P>0.05).The curative effect of the treatment group was similar to that of the control group.(5)CRindex: after treatment,the mean value of CR was 132.43±36.56 in the treatment group and 158.67±55.45 in the control group,the difference between the two groups was statistically significant(P< 0.05).The curative effect of the treatment group was better than that of the control group.(6)BUNindex: after treatment,the average of BUN was 8.36±1.88 in the treatment group and 9.45±2.21 in the control group,the difference between the two groups was statistically significant(P<0.05).The curative effect of the treatment group was better than that of the control group.(7)EGFRindex: after treatment,the mean eGFRwas 51.38 ±17.02 in the treatment group and 42.11 ±16.57 in the control group.The difference between the two groups was statistically significant(P<0.05).The curative effect of the treatment group was better than that of the control group.(8)Lipid-regulating efficacy:the total effective rate of the treatment group was 90%,the total effective rate of the control group was 60%.The treatment group was compared with the control group,the difference was statistically significant(p<0.05),and the curative effect of the treatment group was better than the control group.(9)Symptoms scores:the total effective rate of the treatment group was 93.3g and the total effective rate of the control group was 63.3.The difference between the treatment group and the control group was statistically significant(P < 0.05),and the treatment group was superior to the control group.Conclusion:(1)Treating CKD 3-4 patients with phlegm turbid blood stasis by removing turbidity and removing blood stasis combined with acupoint therapy can effectively improve the LDL-C index of TCU TGN HDL-CU and correct the abnormal metabolism of blood lipids in CKD patients.(2)Removing turbidity and removing blood stasis combined with acupoint pressing can effectively delay the progress of renal function.(3)The method of removing turbidity and removing blood stasis combined with acupoint points obviously alleviated the clinical symptoms of CKD patients.