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The Theoretical Analysis Of AMD Degeneration From Blood And Nutriment Circulate Angle And Retrospective Study About This Disease

Posted on:2019-03-18Degree:MasterType:Thesis
Country:ChinaCandidate:C Q ZhangFull Text:PDF
GTID:2394330548492342Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Age-related macular degeneration(AMD)is one of the most common in the elderly in our over 50 blinding eye disease,one of the clinical manifestations of the blurred vision,deformation,often blocked,retinal hemorrhage,etc.,glass membrane warts,seepage,the different phases according to the different treatments,but clinical effect is limited,easy to relapse and expensive.AMD in ophthalmology of traditional Chinese medicine belongs to the"deep unconscious are","straight" such as music,the category of "blindness",clinical treatment from zang-fu differentiation,the doctor experienced,but "all veins are belong to eye",the eye vascular physiological functions and pathological changes of a direct impact on the occurrence of diseases,is part of the treating ocular fundus disease can not be ignored.On the basis of the tutor professor KangZeFeng inherit and carry forward past research results,combined with years of clinical practice,the innovative put forward "disease" pupil god card system,from the Angle of the mesh network reevaluation of fundus lesions and a variety of symptoms for clinical diagnosis and treatment of ocular fundus disease provides a new train of thought.1.Research purpose:(1)acquisition mentor clinic diagnosis for patients with age-related macular degeneration advanced prescription,the use of auxiliary platform of data mining algorithms to construct,summarizes the tutor's experience,explore formula law,inheritance treatment theory;(2)on the basis of clinical practice,data statistical software is adopted to calculate the efficiency,which provides data support for the "myocardial disease" syndrome.2.Subjects:(1)from August 2015 to August,2017,the advanced AMD patients who were treated by the "myocardial disease" syndrome treatment system in the outpatient clinic screened the 102 patients who met the inclusion criteria,and the total number of patients was 350.(2)a total of 51 patients who had been treated for 3 months(and above)were selected.3 research methods:(1)the inheritance of traditional Chinese medicine auxiliary platform software provides rules analysis,complex system entropy and entropy of unsupervised clustering hierarchy clustering algorithm in data mining,such as medical record information entry system will be selected to meet the requirements,including basic information(name,gender,age,clinical time),medical history(chief complaint,hpi,tongue veins),diagnosis,diagnosis of traditional Chinese medicine,western medicine diagnosis,therapy and TCM syndrome differentiation,therapeutic principle and prescription,etc.)entry,analysis of the patient's general information,prescription drug use,drug related,access to medicines frequency,classification,the result of the combination,New Zealand and other core medicine;(2)SPSS20.0 software was adopted,and the independent sample t test was adopted for comparison between groups,and the difference between P<0.05 was statistically significant.4.Research results:(1)the mean age of the enrolled patients was 66.55 + 6.71 years old,and the maximum proportion of 60 to 75 years old was 46%;The oldest is 86 and the youngest is 50.38%of men;Women make up 62%;The patient's visual acuity was 41 people,accounting for 40%.The symptoms of the patients with advanced stage were relatively concentrated,with the most frequency of blurred syndrome at 16%.The number of patients with liver and kidney failure was 41.2%.A maximum of 60.7%of the tongue is red.A maximum of 60.8%of the liverworts.This is a total of 182 Chinese traditional Chinese medicine,and the first six of them are angelica,main glycyrrhiza,poria cocos,half summer,firewood and cassia twig.Four gas analysis:the temperature drug accounted for 36%;Cold drugs accounted for 33%;Analysis of five tastes:the total amount of liquors is 3098 times,accounting for 35%;The xinxiang drug was 2524 times,accounting for 29%;Analysis:22%of the drugs were admitted to the liver.The number of drugs in the spleen was 15%;The drugs used in the kidney were 14%.Set the support level 70 and the confidence 0.9,to get the more commonly used drugs:angelica-poria,midsummer-angelica,midsummer-poria,angelica-cassia,midsummer-half-branches,Chinese wolfberry-bombyx mori;Correlation analysis:the drug such as rhizoma ligustici wallichii-? pinellia,angelica-?pinellia,pinellia tuber-? batryticated silkworm,astragalus-? angelica,astragalus membranaceus-? batryticated silkworm,medlar-? barbed skullcap herb,cattail pollen-? barbed skullcap herb,etc.2,8,according to the relevant punishment degree of clustering 3-5 flavour is the core of drug combination,is one of the more common are:teng-mulberry leaf-radix achyranthis bidentatae,scorpion-teng-notopterygium,scorpion-wind-notopterygium,radix asparagi-ChuShi son-stone calamus,Fried amomum villosom-alisma cortex phellodendri.Combination at the same time,the extraction of 4 first New Zealand:(1)sichuan fruit,windproof,radix geutianae,scorpion,notopterygium,(2)sichuan fruit,Fried gardenia silver radix bupleuri,radix geutianae,caulis spatholobi,(3)the root of remembranous milk vetch,turmeric,triangular,rehmannia glutinosa,copus,alisma(4)to skin and bones,radix paeoniae rubra,rhizoma polygonati,caulis spatholobi,radix bupleuri silver(2)the average visual acuity of the patients was increased from 0.12 + 0.07 to 0.31 +0.12,and p?0.05 was statistically significant,from the visual acuity,the thickness of the macular center and the leakage area of FFA.The average value of the concave thickness of the macular center was reduced from 489.40 + 70.04 to 176.91,and the thickness of the macular center was statistically significant.FFA contrast showed an effective(effective + effective)rate of 86.27%,and the best corrected visual acuity(effective + effective)rate was 92.16%.5 conclusion(1),a study shows,along with the age growth,the ratio of male and female patients was 1.44:1,but clinical Yang deficiency,phlegm wet mass and the incidence of heart dysfunction group is more obvious,and women pay more attention to early symptoms and small lesions,so the clinical finding more female patients.(2)evil resistance is result in mesh network,network to be virtual,nearly and the core of pupil god disease etiology and pathogenesis,drug core medicine composition and correlation analysis,found that more than for t2dm medicine phase must,phase.(3)"tongmu luo,qi qi and Yin qi" is the general rule of the eye contact disease,and it is often used in the new composition of tongluo to invigorate Yin and Yang.(4)the prescription drug effect under the guidance of the "myoclosis" syndrome is obvious,the eyesight is improved,and the bleeding and bleeding are absorbed,which can provide quantitative evidence support for the system.
Keywords/Search Tags:Diagnosis and treatment from blood and nutriment circulate, Age-related macular degeneration, Traditional Chinese medicine inheritance auxiliary platform, Data mining
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