| Objectives To understand the influence of type 2 diabetes on the thickness of epicardial adipose tissue and the clinical significance of EAT measurement,and to provide new ideas for the prevention and treatment of type 2 diabetes complicated by cardiovascular disease..Methods The patients who were treated in the affiliated hospital of North China University of Science and Technology from December 2016 to December 2017 were selected as the study subjects,of whom type 2 diabetes was a case group and the healthy checkup group was a control group.All subjects were measured and recorded for their height,weight,blood pressure,and pertinence by asking previous medical history and calculating body mass index(BMI).Absorption of fasting blood to fasting blood glucose,triglyceride(TG),total cholesterol(TC),Low Density Lipoprotein(LDL),High Density Lipoprotein(HDL)Blood uric acid for laboratory tests.An ultrasound chamber physician in our hospital performed color ultrasound examination on the six vessels of the patient's neck and performed a plain scan on the patient's chest using a Philips 256-slice spiral CT.An experienced CT radiologist from the hospital was selected to treat the patient.Chest CT plain scan results were reviewed and the adipose tissue CT value was set to-90~-15 Hu.Select 25%,50%,75% of the free wall of the right ventricle,the atrioventricular sulcus,the left ventricular apex and the atrioventricular groove right canthal area for epicardial adipose tissue(EAT)thickness Measure and take the average of the two measurement planes.SPSS17.0 was used for statistical analysis.T-tests were used to compare the two independent sample measurement data.Chi-square test was used to compare the count data.Logistic regression analysis was used to screen risk factors for EAT thickening,and different parts were evaluated by ROC curve.Clinical significance of EAT thickness measurement in type 2 diabetic patients complicated with coronary heart disease..Results A total of 203 subjects were studied,with an average age of 61.13±10.64 years.118 patients with type 2 diabetes were in the case group.There were 55 males,63 females and 64 coronary heart disease patients in the case group.85 cases of healthy examiners in the same period were in the control group,and 42 cases were in the control group and 43 were females.The composition ratios of BMI,fasting blood glucose,TG,LDL,uric acid,SBP,and cervical vascular lesions were significantly higher in the case group than in the control group,and HDL was significantly lower than that in the control group(P<0.05).There was no significant difference in age,gender,TC and DBP between the two groups(P>0.05).The composition ratio of EAT thickness and EAT thickening was significantly higher in the case group than in the control group,and the risk of EAT thickening in the case group was approximately 5 times greater than that in the control group.Excluding other indicators,type 2 diabetes remained a risk factor for EAT thickening(OR=8.760,95%CI: 2.321-33.063,P=0.001).At the same time,elevated BMI and TG levels were also risk factors for increased EAT thickness(OR1=2.614,95%CI1: 1.067-6.403,P1=0.035;OR2=5.871,95%CI2: 2.370-14.548,P2<0.01).The increase in HDL was a protective factor for increased EAT thickness(OR=-0.211,95%CI: 0.075-0.593,P=0.003).Patients with type 2 diabetes mellitus complicated with coronary artery disease were found in the left coronary region and atrioventricular ditch The EAT thickness at the free wall of the coronary and right ventricle was higher than that of the simple type 2 diabetes group,and the difference was statistically significant(P<0.01).However,the EAT thickness of the left ventricular apex was not significantly different between the two groups(P>0.05).The EAT thickness in the right canopy area of AVG is better than that of other locations in the prediction of CAD in type 2 diabetes(and,when the EAT thickness in the right canal area is 1.155cm),type 2 diabetes mellitus with coronary heart disease has better sensitivity.And specificity(AUC=0.849,sensitivity 84.4%,specificity 77.8%,95% CI: 0.77-0.91)).Conclusions Type 2 diabetes has an increased epicardial fat thickness compared to healthy individuals.Type 2 diabetes increases the risk of EAT thickening.Measurement of EAT thickness 1.155 cm in the right atrioventricular sulcus by 256-slice spiral computed to predict type 2 diabetes mellitus Heart disease patients have better sensitivity and specificity. |
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