Endoscopic Performance Of Inflammatory Bowel Disease And The Relevance Of TCM Syndrome Types Research

ObjectiveTo investigate the correlation between different TCM syndromes and endoscopic mucosal images of Inflammatory Bowel Disease,summarize the characteristics of TCM syndromes and the internal law of their performance under the colonoscopy,and provides more objective and scientific basis for TCM syndrome differentiation of IBD.MethodsCollecting clinical data of IBD inpatients,225 cases of IBD met the inclusion criteria and exclusion criteria were selected in the clinic,design a clinical questionnaire according to the research idea.Then,to summarize and analyze the patient’s general data,clinical manifestations,four diagnostic materials,the microscopic performance under colonoscopy or enteroscopy,and to enter the data.SPSS 18.0 statistical software was used for statistical processing to reach the conclusion.ResultsFirst,125 cases of IBD were collected,including 104 cases of CD patients and 121 patients with UC.In terms of gender distribution,CD is predominantly male,66.3%;And UC,Men accounted for 55.4% and women 44.6%.In the age distribution,CD was mostly middle-aged,and 82.7% in 17-40 years old.In the case of UC,40.5% were aged between 17 and 40 years old,and 59.5% were older than 40 years old.In the course of disease distribution,both of the patients had a longer course of disease,and the CD patients with more than 3 years of disease accounted for 39.5%,and UC accounted for 39.7%.Second,In terms of the distribution of syndromes,CD is more common in spleen-stomach deficient cold pattern and damp heat retention,and UC is more common in spleen deficiency and dampness-heat syndrome、spleen deficiency and dampness syndrome and large intestinal damp-heat.In terms of stage of CD,the activity period and the remission period were all in proportion to the spleen-stomach deficient(P>0.05).The activity period of UC is more common with spleen deficiency and dampness-heat syndrome、large intestinal damp-heat,but spleen deficiency and dampness syndrome is more in the remission period(P<0.05).There was no correlation between the lesions and the distribution of TCM syndromes(P>0.05).In addition,the damp heat retention are prone to perianal disease(P<0.05).Third,Under the mirror: CD patient,the positive rate of intestinal mucosal bleeding is the highest in the syndrome of spleen-stomach deficient cold pattern,more than the spleen deficiency and dampness-heat syndrome 、 syndrome of cold-dampness disturbing spleen 、 the Liver depression and Spleen deficiency(P<0.05).The paving stones change more in liver stagnation and spleen deficiency,and there is a significant difference between damp heat retention(P<0.01),but with other syndromes there are no significant difference(P > 0.05).There is a large probability of the occurrence of intestinal polyps in syndrome of cold-dampness disturbing spleen,and the difference of liver depression and spleen deficiency is statistically significant(P<0.05).There was a high positive rate of intestinal stenosis in spleen-stomach deficient cold pattern 、 spleen deficiency and dampness-heat syndrome,and the difference of damp heat retention and the Liver depression and Spleen deficiency was statistically significant(P<0.05).In the ulcer moss,yellow moss is mainly composed of damp heat retention,while white moss is mainly characterized by spleen-stomach deficient cold pattern.There was no difference in the distribution of TCM syndromes in ulcers,hyperemia,edema and mucosal erosion.In the aspect of ulcerative colitis,the possibility of ulceration in the large intestinal damp-heat、syndrome of intermingled heat and coldwas significant(P<0.05).In addition to the yang deficiency of spleen and kidney,other TCM syndromes are more likely to appear mucosal hyperemia and texture fuzzy,but the difference was not statistically significant.(P<0.05).There is a significant difference between large intestinal damp-heat、spleen deficiency and dampness-heat syndrome with spleen deficiency and dampness syndrome(P<0.05).The disappearance of colon bag more appear in the spleen deficiency and dampness-heat syndrome than large intestinal damp-heat、spleen deficiency and dampness syndrome(P<0.05).In the ulcer moss,the yellow moss is mainly based on spleen deficiency and dampness-heat syndrome、the large intestinal damp-heat,while white moss is mainly composed of the spleen deficiency and dampness syndrome、syndrome of intermingled heat and cold(P<0.05).But there was no difference in the distribution of TCM syndromes in mucosal erosion,mucosal hyperemia,bleeding color,purulent secretion,and intestinal stenosis.ConclusionThe different TCM syndromes of IBD patients have certain correlation with the performance of colonoscopy.And,There are differences in TCM syndromes、relationship with performance under colonoscopy between CD and UC.There is a obvious correlation between the different TCM syndrome type of CD,including mucosal bleeding、mossy color、paving stones change、intestinal polyps and intestinal stenosis.But UC is related to mucosal hyperemia、texture fuzzy、ulcer、mossy color、intestinal polyps and the disappearance of colon bag.Among them,CD patients with spleen-stomach deficient cold pattern prone to mucosal hyperemia and intestinal stenosis,the damp heat retention are prone to perianal disease.The hot syndrome of UC patients can easily form ulcers;The formation of intestinal polyps in IBD is closely related to the damp evil.The color of the moss of ulcer in IBD is related to cold and heat syndrome.The white moss are found in the cold,and the hot yellow moss is often found in the heat.