Study On Correlation Between TCM Syndrome Types And Laboratory Indexes In Patients With Inflammatory Bowel Disease

ObjectiveTo explore the relationship between TCM syndromes and laboratory indexes of ulcerative colitis(UC)and Crohn’s disease(CD)in order to seek out regularities between them and provide some objective basis for clinical syndrome differentiation of TCM.MethodsSelecting patients with UC and CD from medical record system.These patients were classified into two groups:remission and active stag.UC were classified into seven groups:large intestine damp-heat syndrome,water retention due to hypofunction of the spleen,liver depression and Spleen deficiency,syndrome of intermingled heat and cold,yang deficiency of spleen and kidney,spleen deficiency and dampness-heat syndrome,deficiency of yin-blood.CD were classified into six groups:deficiency cold of spleen and stomach syndrome,spleen deficiency and dampness-heat syndrome,han-shi staying in spleen,damp-heat retention,liver depression and Spleen deficiency,type of qi stagnation and blood stasis.Collecting materials about sex,age,ESR,CRP,Hemoglobin,albumin,platelet count,of these patients.After recording all materials,we analyze related index through the statistical methods.Comparing the different of TCM Syndrome Types between remission and activity of UC and CD through the change of laboratory indexes.ResultsUC This study collected 180 patients with ulcerative colitis.The most common TCM syndrome type is spleen deficiency and dampness-heat syndrome.The most common TCM syndrome type of remission is water retention due to hypofunction of the spleen,and the most common TCM syndrome type of activity is spleen deficiency and dampness-heat syndrome.The distribution of TCM syndrome types and platelet counthave obvious correlation(P<0.05)inremission:the people who belongs to large intestine damp-heat syndrome,platelet count increased most obviously.The distribution of TCM syndrome types and CRP obvious correlation(P<0.05)in activity:the people who belongs to liver depression and Spleen deficiency,CRP increased most obviously.The distribution of hemoglobin、albumin、ESR and TCM syndrome types have no obvious correlation(P>0.05).CD This study collected 127 patients with CD.The most common TCM syndrome type is deficiency cold of spleen and stomach syndrome.The most common TCM syndrome type of remission and activity is deficiency cold of spleen and stomach syndrome.The distribution of TCM syndrome types and platelet counthave obvious correlation(P<0.05)in remission:the people who belongs to spleen deficiency and dampness-heat syndrome,platelet count increased most obviously.The distribution of TCM syndrome types and Hb obvious correlation(P<0.05)in remission:the people who belongs to liver depression and Spleen deficiency,Hb is the less.The distribution of TCM syndrome types and ESR obvious correlation(P<0.05)in remission:the people who belongs to liver depression and Spleen deficiency,ESR increased most obviously.The distribution of TCM syndrome types and CRP obvious correlation(P<0.05)in remission:the people who belongs tohan-shi staying in spleen,CRP increased most obviously.But liver depression and Spleen deficiency is opposite.The distribution of TCM syndrome types and ESR obvious correlation(P<0.05)in activity:the people who belongs to deficiency cold of spleen and stomach syndrome,ESR increased most obviously.The distribution of TCM syndrome types and CRP obvious correlation(P<0.05)in activity:the people who belongs to cold of spleen and stomach syndrome,CRP increased most obviously.The distribution of hemoglobin and TCM syndrome types have no obvious correlation(P>0.05).ConclusionThis study proves preliminary that there is some correlation between TCM Syndrome Types and laboratory indexes in patients with Inflammatory bowel disease.The change of Hb,platelet counthave,ESR and CRP can reflect the Difference of TCM syndrome types.So laboratory indexes work for TCM Syndrome Types in patients with Inflammatory bowel disease.Albumin Should not be the objective basis of study of TCM syndrome types.