| PurposeThe type constituent ratio,age distribution,sex ratio and other clinical data of the primary glaucoma patients in our hospital were retrospective analyzed to have an understanding of the prevalence of glaucoma in the Jilin region.And the domestic and international research were also compared to explore the possible causes of this disease and provide new epidemiological data for the prevention and treatment of glaucoma in Jilin.MethodsRetrospectively analyze the data from individuals who had been hospitalized in glaucoma department of the second hospital of jilin university from September,2014 to August,2017,Statistically analysis the disease type ratio,age distribution,sex ratio,vision in installment,axial length,anterior chamber depth,preoperative and postoperative visual acuity and intraocular pressure and other clinical data of the primary glaucoma patients.Results1.The composition of primary glaucoma and the variation trend: during the three years,the primary acute angle-closure glaucoma(aPACG),the primary chronic angle-closure glaucoma(cPACG)and the primary open-angle glaucoma(POAG)was accounted for 61.05%?32.35% and 6.60% of the total number of the primary glaucoma patients,respectively,with the ratio of aPACG,cPACG and POAG being 9.26: 4.91: 1.There was no significant change in the composition ratio of disease types in primary glaucoma patients during the 3 years we analyzed.2.The correlation between the prevalence of the primary glaucoma and seasons: The number of patients with aPACG,cPACG,and POAG during the three-year winter period(November,December,and January)was 398,171,and 27,respectively,while,during the summer(June,July,and August)the number was 282,159,and 24.APACG,cPACG,and POAG patients in winter and summer accounted for 33.59% and 24.80%,27.23%,and 25.32%,21.09%,and 18.75% of the total number of patients with the disease.The accumulative number of aPACG patients in the winter and the total number of patients in the three-year period were significantly higher than in summer.The cumulative number of patients with cPACG and POAG was similar in winter and summer.3.The relationship between the primary glaucoma and gender: the ratio of male and female patients in the primary glaucoma was 1: 95.While the ratio of male and female patients in the a PACG,cPACG and POAG patients were 1:3.2,1:1.14 and 1:0.54,respectively.The disease of PACG affected women more often than men,especially in aPACG,the incidence of aPACG among women are more than three times than men,while for POAG,the male cases were much more than females.The Chi-square test of the composition of the three types of primary glaucoma patients was statistically significant(?2=155.30,P<0.001).4.The relationship between primary glaucoma and age: The average age,concentration and discrete trend were represented with M(P25,P75).The M(P25,P75)of the three diseases were 65(60,70),64(58,69)and 56(43,64)years old respectively.The differences were statistically significant between the two,indicating the average age of the disease: aPACG > cPACG > POAG.Compared with aPACG and cPACG,the four quantile spacing Q(P75-P25)of POAG patients was larger(21)and the median(M)was relatively small(56 years old),indicating that the age of POAG is relatively younger and the age distribution is relatively discrete,while aPACG and cPACG are older and the age distribution is more concentrated.The majority of primary glaucoma were over 40 years of age,?40-year-old aPACG,cPACG and POAG accounted for 99.49%,99.68%,82.03% of the total number of patients respectively,and patients aged ?50 accounted for 95.61%,94.75% and 63.28% respectively.The age of patients with aPACG and cPACG mainly concentrated in the 50~80 years old,accounting for 91.65% and 92.03% respectively.Among them,the number of patients in the 60~70 years old was the highest,accounting for 47.51% and 46.58% respectively.For POAG patients,there is a large number of people in the 50-70 age range,accounting for 47.66%,but it was not as concentrated as the distribution of PACG.5.Stage difference of preoperative visual field for primary glaucoma patients: the ratio of severe visual field defect(MD?-12dB)among the aPACG?cPACG and POAG hospitalized patients was 66.58%,77.6%and 88.28%,respectively,indicating that POAG and cPACG patients had a severe visual field defect.6.The axial length differences of the patients with primary glaucoma: The M(P25,P75)of axial length of the aPACG ? cPACG and POAG patients was 22.23(21.74,22.80)mm ? 22.62(22.07,23.11)mm ? 23.58(22.84,24.45)mm,respectively.And the average axial length of the three kinds of disease followed the sequence of POAG > cPACG > aPACG.7.The differences in anterior chamber depth of primary glaucoma patients: The M(P25,P75)of anterior chamber depth of the aPACG?cPACG and POAG patients was 1.71(1.54,1.87)mm?1.94(1.78,2.11)mm?2.91(2.54,3.17)mm,respectively.And the average axial length of the three kinds of disease followed the sequence of POAG > cPACG > aPACG.8.The characteristics of the vision of the primary glaucoma patients in hospitalization and discharging: During the 3 years,the blindness rate of primary glaucoma patients before and after operation was aPACG 50.13% and 32.41%,cPACG 47.29% and 44.74%,POAG 51.56%,respectively.Compared with preoperative,the blindness of aPACG patients decreased by 17.72%,and the difference was statistically significant.The rate of blindness of cPACG and POAG patients did not change significantly.It shows that the average postoperative visual acuity of aPACG patients is higher than that of admission,while the average discharged visual acuity of cPACG and POAG patients is not significantly different from that of preoperative.9.The characteristics of the intraocular pressure of the primary glaucoma patients in hospitalization and discharging: The intraocular pressure of PACG and POAG patients were significantly lower than those before operation,and the difference was statistically significant.Conclusion1.In the last three years,the primary glaucoma patients in our hospital was mainly composed of PACG.Among them,the largest proportion of patients is aPACG,followed by cPACG,and the proportion of POAG was still small.The composition of the three kinds of primary glaucoma patients did not change significantly.2.The incidence of the aPACG was seasonal.The number of patients suffering from winter was significantly higher than that in summer;while the cPACG and POAG incidence is of no obvious seasonal.3.Women are more susceptible to PACG than men,especially aPACG.POAG is more common in men than in women.The age distribution of POAG patients is not as concentrated as that of PACG patients,and the disease age is relatively young.The population under the age of 40 should pay attention to the prevention and treatment of POAG,when over 40 should pay attention to the prevention and treatment of PACG.4.Among patients with primary glaucoma in our hospital,POAG patients had the greatest visual impairment,followed by cPACG.The visual field damage was relatively mild in patients with aPACG.This is related to the atypical clinical symptoms and signs of POAG and cPACG.5.Axial length and anterior chamber depth have a certain correlation with the incidence of glaucoma.6.The average postoperative visual acuity of aPACG patients in our hospital was improved compared with that before operation,and the rate of blindness was decreased.The average postoperative visual acuity and the rate of blindness of POAG patients were not significantly different from those before operation.7.The postoperative intraocular pressure of primary glaucoma patients were significantly lower than those before operation. |
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