Distribution Of Traditional Chinese Medicine Syndromes Of Chronic Atrophic Gastritis And Its Correlation

Objective: Through a retrospective study,to explore the distribution of TCM syndromes in chronic atrophic gastritis(CAG),and to further analyze the intrinsic changes of relevant factors affecting TCM syndromes.To provide a theoretical basis for clinical diagnosis and treatment of CAG.Methods: Data of 152 inpatients with CAG as the first clinical diagnosis were collected from the Affiliated Hospital of Changchun University of Traditional Chinese Medicine from June 2013 to August 2017.The distribution of CAG TCM syndromes,age,hospitalization days and other factors were described and correlated.Results:1.152 cases of CAG,the ratio of male to female was 1:1,and the incidence rate of women over 70 years old was higher than that of men(P < 0.05).2.Distribution of TCM syndromes: Gastric collateral stasis syndrome(62 cases,40.8%)> Liver-stomach Disharmony Syndrome(52 cases,34.2%)> Spleen-stomach dampness-heat syndrome(22 cases,14.5%)> Spleen-stomach weakness syndrome(11cases,7.2%)> Liver-stomach stagnation-heat syndrome(3 cases,2.0%)> Gastric Yin deficiency syndrome(2 cases,1.3%);There was a significant difference in the distribution of each syndrome type(P < 0.01).3.The longest history of CAG was 360 months,with a median of 11 months.There was a significant difference in the course distribution of CAG(P < 0 01).4.The longest hospitalization days of CAG were 29 days,with a median of 13 days.Gastric collateral blood stasis syndrome(14.00 ± 5.45 days),liver-stomach disharmony syndrome(12.04±5.28 days),spleen-stomach dampness-heat syndrome(12.27±5.57 days),spleen-stomach weakness syndrome(9.73 ± 3.47 days).There was statistical difference between the syndrome of blood stasis of stomach collaterals and the syndrome of weakness of spleen and stomach(P < 0.05).5.In gastroscopy,the red-white phase of gastric mucosa accounted for 97.35%;mucosalcongestion accounted for 89.40%;mucosal edema accounted for 78.15%;mucosal thinning(vascular exposure)accounted for 62.25%;rough mucosa accounted for45.03%;nodular accounted for 19.21%.There were significant differences in common gastroscopic images of CAG,P<0.01.In gastroscopy,the detection rate of white phase of mucosa was the highest in spleen-stomach weakness syndrome and spleen-stomach dampness-heat syndrome.The detection rate of weakness of Spleen-stomach was the highest in mucosa thinning(blood vessel exposure).The detection rate of blood stasis in gastric collaterals was the highest in rough mucosa,and that of disharmony between liver and stomach was the highest in nodular mucosa.There was no significant difference in the incidence of gastroscopic factors between men and women(P>0.05).There was no significant difference in the total score of gastroscopy between the sexes(P>0.05).The total score of gastroscopy in spleen-stomach weakness syndrome was the highest(6.45points),while that in spleen-stomach dampness-heat syndrome was the lowest(5.86points).There was no statistical difference among the syndromes(P>0.05).6.The incidence of the disease in four seasons: spring > summer > winter > autumn.Liver-stomach disharmony syndrome occurs in spring and summer;spleen-stomach weakness syndrome occurs in winter;spleen-stomach dampness-heat syndrome occurs in summer and autumn;stomach collateral stasis syndrome occurs in winter and spring.7.The average days of hospitalization of weifening granules in patients with pi-wei damp-heat syndrome were 10.89±6.47 days and 13.23±4.90 days(P=0.209>0.05).The average days of hospitalization in patients with gastric collatar-stasis syndrome were 13.49± 5.39 and 14.67 ± 5.55(P=0.347>0.05).Weifuning granule can shorten the treatment period of stomach collaterals blood stasis and damp-heat of spleen and stomach.8.The utilization rate of collapsing painkiller prescription combined with infrared irradiation for CAG patients was 90.79%.Conclusion:1.The distribution of CAG syndromes in traditional Chinese medicine is the most with stomach collaterals stasis and the least with deficiency of stomach Yin.There was a certaincorrelation between TCM syndrome type and the patient's gastroscopy image,length of stay and disease season.There was no correlation between the distribution of TCM syndromes of CAG and age and gender.The morbidity of male and female patients in the same age group was different.2.Weifuning Granule,a hospital preparation,can shorten the treatment cycle of gastrointestinal blood stasis syndrome and spleen-stomach dampness-heat syndrome.It has the effect of treating CAG with the combination of traditional Chinese medicine and infrared irradiation.