| objectiveThis topic aims to ask the correlation between the syndrome differentiation and HP infection of chronic atrophic gastritis by comprehensively collecting and statistical clinical data,and to summarize the pattern of traditional Chinese medicine(TCM)patterns of chronic atrophic gastritis and the pathogenesis of HP infection,so as to provide more objective basis for the clinical diagnosis and treatment of this disease.MethodTwo hundred patients from the Department of splenogastric diseases,Nanjing Hospital of traditional chinese medicine,affiliated to nanhuan university of chinese medicine,Nanjing,China,who were hospitalized and outpatient diagnosed with chronic atrophic gastritis by gastroscopy and pathological examination between September 2018 and February 2021,were selected for the study.The data on patients’ general information,information on four diagnoses of traditional Chinese medicine,and results of HP tests were collected and reviewed by two physicians above using traditional syndrome differentiation methodsConsistent with TCM syndrome differentiation and differentiation.All the obtained data were analyzed using spss26.0 statistical software to ask the correlation between each syndrome type of TCM and gastroscope image and HP infection.result(1)A total of 200 patients with chronic atrophic gastritis,79 males and 121 females,with an age interval of 30-86 years,were included in this study.chronic atrophic gastritis has the highest incidence of 38%in patients aged 60 to 69 years regardless of both sexes,followed by 30%in those aged 50 to 59 years,and the lowest incidence of 4%in those aged 30 to 39 years.After x2 test,the results showed obvious differences in the age distribution.Over 50%of the detected clinical symptoms in TCM(TCM)are epigastric distress,epigastric fullness,epigastric dull pain,noisy,eructation,distension and even after eating,poor nose,and irritability.It suggested that the CSG patients were mainly middle-aged and young adults,and epigen distension was the most common clinical symptom.(2)The frequency of six TCM Patterns in 200 chronic atrophic gastritis patients included in the study was as follows:spleen and stomach weakness>liver and stomach qi stagnation>spleen and stomach dampness>liver and stomach depression>stomach yin deficiency>gastric collaterals stasis.It is suggested that chronic atrophic gastritis spleen stomach weakness syndrome is the most,gastric collaterals stasis syndrome is the least.(3)In TCM,the infection rate of HP of each syndrome was in the order from high to low:spleen and stomach dampness>liver and stomach depression>spleen and stomach weakness>stomach yin deficiency>stomach collaterals stasis>liver and stomach qi stagnation.It suggested that chronic atrophic gastritis spleen stomach dampness heat syndrome had the highest proportion of infection with HP.(4)In 200 patients with chronic atrophic gastritis selected for this study,the tongue was predominantly pale red(34.5%),followed by tongue fat(30%),often coexisting with the presence of dentate marks(29%)on the edge of the tongue body,the tongue reddish(24%),and the remaining kinds of tongue substance such as dark red,petechial ecchymoses,thin,crackles were less frequently observed.The proportion of the type of tongue coating exhibited by the patients ranged from high to low in the following order:white>yellow>greasy=thick>less>dry>smooth.The order of percentage of each pulse in the 200 patients with chronic atrophic gastritis from highest to lowest was as follows:thin>sink>weak>string>slow>slip>number>jerky.conclusionEach TCM syndrome type of chronic atrophic gastritis has a certain distribution rule,and there is a certain correlation and disease rule between each syndrome type of HP infection.(1)The most common TCM syndrome type of chronic atrophic gastritis is weakness of spleen and stomach,followed by stagnation of liver and stomach qi,and the smallest proportion is blood stasis of stomach collaterals.(2)The positive rate of HP infection was the highest in spleen stomach damp heat syndrome,and the lowest in liver stomach qi stagnation syndrome.(3)The clinical symptoms of chronic atrophic gastritis are epigastric fullness,anorexia,epigastric pain and epigastric pain.The main pulse condition is small pulse,and the least is astringent pulse.It can provide more accurate basis for syndrome differentiation combined with specific gastric mucosa morphology under gastroscope,and better serve for clinical treatment. |