Correlative Factors Analysis Of Lymphatic Metastasis And Five-year Survival Rate For Cervical Cancer Of Stage Ⅰ-Ⅱ

Objective: To explore the high risk factors for lymph node metastasis of cervical cancer and the influencing factors of 5-year survival rate after radical surgery.Method: Retrospectively reviewed the medical records of FIGO stage Ⅰ-Ⅱ cervical cancer patients from January 2012 to February 2014 in First Affiliated Hospital of Chongqing Medical University.A total of 145 patients underwent radical hysterectomy were included.The clinical,serological,pathological and follow-up data were collected for univariate and multivariate analysis.Results: The lymphatic metastasis rate of patients with FIGO stage ⅡA2-ⅡB,larger lesion(≥2 cm),deeper invasion(≥2/3),positive vessel,higher SCC(≥2μg/L)was higher than that of patients with ⅠA-ⅡA1 stage,lesion <2 cm,superficial invasion(≤ 1/3),negative vessel and SCC<2μg/L.The depth of invasion was an independent influencing factor for lymphatic metastasis(P < 0.05).Preoperative SCC,positive vessel and lymphatic metastasis were closely related to the 5-year survival rate afteroperation,the 5-year survival rate of patients with higher SCC(≥2μg/L),positive vessel,and lymphatic metastasis was lower than that of patients with SCC <2μg/L,negative vessel and negative lymph nodes.The lymphatic metastasis was an independent influencing factor for 5-year survival of cervical cancer.Conclusion: The depth of invasion was an independent influencing factor for lymphatic metastasis.The lymphatic metastasis rate of patients with deep invasion was significantly higher than that with superficial invasion.The level of SCC before treatment,vessel invasion and the lymphatic metastasis significantly affect the 5-year survival rate of patients with cervical cancer after operation.