Clinical Observation Of Treatment Of Chronic Pelvic Inflammatory Disease With Mongolian Medicine Combined With NiRuHa Therapy

Objective: 1.Observe the improvement in lower abdominal pain,lumbosacral pain,excessive leucorrhea,emotional depression and irritability,and the influence of gynecological color Doppler ultrasound,HR and ESR examinations.To objectively evaluate the clinical efficacy of Mongolian medicine combined with Niruha in the treatment of chronic pelvic inflammation(CPID),and to preliminarily evaluate the safety,so as to provide useful reference for clinical practice.Methods: A total of 91 patients who met the diagnostic criteria and inclusion criteria of CPID in the Gynecological Clinic of Inner Mongolia Autonomous Region International Mongolian Medical Hospital from November 2017 to January 2019 were randomly divided into observation group(30 cases),control group I(31 cases)and control group II(30 cases).The observation group was treated with oral administration of Su Ge Mu Le-7,Tong La Ga-5,Amin Er Dun,etc.SHa Ri Ga-4 soup(5g)was enema.The control group I received oral administration of Su Ge Mu Le-7,Tong La Ga-5,Amin Er Dun and other drugs.The control group II received oral ornidazole dispersible tablets and amoxicillin capsules for half a month,and all patients were treated for one course of treatment.The symptoms and signs of each patient before and after treatment were scored,and the gynecological color ultrasound and HR and ESR were compared before and after treatment.The data were processed using SPSS 22.0 statistical software.Results: 1.Comparison of effective rate among:(1)Total effective rate: In observation group the effective rate was 86.67%.In control group I the effective rate was 67.74%.In control group II the effective rate was 83.33%.There was a statistically significant difference among the three groups(P<0.05).(2)The total effective rate of symptoms: In observation group the effective rate was 93.33%.In control group I the effective rate was 64.52%.In control group II the effective rate was 83.33%.The observation group and the control group I had statistical significance(P<0.05),and the effective rate of the observation group and the control group II had no statistical significance(P>0.05).(3)Total effective rate of physical signs: In observation group the effective rate was 70.00%.In control group I the effective rate was 54.84%.In control group II the effective rate was 63.33%.There was statistical significance among the three groups(P<0.05).2.Comparison of symptoms and signs before and after treatment among the :(1)Comparison of symptoms: In observation group,the lower abdominal pain,lumbosacral pain,leucorrhea,emotional depression and irritability,dark red menstrual color or blood clots and other symptoms before and after treatment had statistically significant differences(P<0.01).There was no statistical significance in hypothermia before and after treatment(P>0.05).In control group,there were significant differences in the symptoms of lumbosacral pain,emotional depression and irritability before and after treatment(P<0.05).There were significant differences in the lower abdominal pain and vaginal discharge before and after treatment(P<0.01),and there was no statistical significance in the symptoms of hypothermia,dark red menstrual color or blood clots before and after treatment(P>0.05).There were significant differences in control group II in depression and irritability,dark red menstrual color or blood clots before and after treatment(P<0.05),lower abdominal pain,lumbosacral pain,leucorrhea and other symptoms before and after treatment(P<0.01).There was no statistical significance in hypothermia before and after treatment(P>0.05 .(2)Comparison of symptoms: There were differences in the inflammatory mass of the double-appendix area of the observation group before and after treatment(P<0.05),and the uterus was limited or tender,and the double-appendix area was thickened or tendered.The difference was statistically significant(P<001).There was no statistically significant difference in the signs of thickening and tenderness of the palpebral ligament(P>0.05).In the control group,there was a difference in uterine activity or tenderness,which was statistically significant(P<0.05).There was no difference in the thickening or tenderness of the double-appendix area,the inflammatory mass in the double-appendix area,and the thickening and tenderness of the uterine ligament(P>0.05).There were significant differences in the thickening or tenderness signs of the control group II in the double-appendix area before and after treatment(P<0.05).There were statistically significant differences in the symptoms of uterine activity restriction or tenderness and inflammatory mass in the doubleappendix area(P<0.01),and no statistically significant difference before and after treatment of uterine ligament ligament and tenderness(P>0.05).3.Comparison of auxiliary examinations among :(1)Comparison of three groups of gynecological color Doppler ultrasound treatment: There were statistically significant differences in the comparison of gynecological color ultrasound before and after treatment in the three groups(P<0.01).Compared with control group I and control group II,there were significant differences among the three groups(P<0.05).There was no statistically significant difference between control group I and control group II(P>0.05).(2)Comparison of HR and ESR before and after treatment among three groups: The whole blood high-shear reduced viscosity,whole blood low-shear reduced viscosity,PCV,ηb in the observation group were different before and after treatment,which was statistically significant(P<0.05).ESR treatment had significant differences before and after treatment,which were statistically significant(P<0.01).The highshear reduced viscosity,PCV and ηb in control group I were significantly different before and after treatment(P<0.05).There was no significant difference between the whole blood low-shear reduced viscosity and ESR before and after treatment(P>0.05).The whole blood low-shear reduced viscosity in control group II was different before and after treatment(P<0.05),and there was significant difference in ESR before and after treatment(P<0.01).There was no difference in whole blood highshear reduced viscosity,PCV and ηb before and after treatment,no statistical significance(P>0.05).4.Comparison of side effects: There were no obvious side effects in observation group and control group I.Two patients in control group II had nausea and other side effects.There was no significant difference among the three groups(P > 0.05).Conclusion: Mongolian medicine combined with niruha has a significant effect in treating mild and moderate chronic pelvic inflammatory disease.Especially for chronic pelvic inflammatory disease(CPID)lower abdominal pain,lumbosacral pain,leucorrhea and other symptoms and limited uterine activity,bilateral adnexal thickening,bilateral adnexal inflammatory mass and other signs are particularly effective.And fewer side effects,so it is worthy of further clinical application.