| Objective:Taking heat-sensitive moxibustion for the treatment of benign prostatic hyperplasia(BPH)as an example,the relationship between the intensity of heat-sensitive moxibustion and the effect of moxibustion was observed according to different intensity of moxibustion sensation,so as to provide objective basis for clinical treatment of heat-sensitive moxibustion.Methods:Fifty-four eligible BPH subjects were enrolled and treated with heat-sensitive moxibustion twice a day for the first six days.The subjects were divided into heat-sensitive moxibustion group A and heat-sensitive moxibustion group B according to the overall evaluation of the intensity of moxibustion.There were 31 cases in group A and 23 cases in group B.Then each group was treated with heatsensitive moxibustion for 20 days,once a day,each time with the degree of disappearance of moxibustion sensation.The International Prostate Symptom Scale(IPSS),Quality of Life Scale(QOL),Maximum Urinary Flow Rate(Qmax)and Bladder Residual Urinary Volume(RUV)were observed.To observe the clinical efficacy of two groups of subjects before treatment,after treatment and 2 months after treatment,and to explore the relationship between the intensity of moxibustion sensation and the effect of moxibustion.Results:1.Baseline comparison: There were no significant differences in age,body weight,mean disease duration,prostate volume,IPSS,QOL,Qmax,and RUV between the two groups before treatment(P>0.05),which were comparable.2.Frequency statistics of heat-sensitive acupoints: Among the five acupoints explored,the frequency of heat-sensing of acupoints was Zhongji(25,46.2%),Guanyuan(20,44.4%),and Mingmen(18,33.3%),Shenshu points(8,18.5%),secondary acupoints(7,16.7%).Through multiple comparisons of sample rates,the frequency of heat in the acupoints of Zhongji and Guanyuan points was higher than that of Shenshu and Ciyu(P<0.05),while the heat of acupoints between Zhongji and Guanyuan points There was no significant difference in the rate(P>0.05).3.Comparison of curative effect: There were significant differences in QOL score,IPSS score,RUV and Qmax between the two groups before and after the heat-sensitive moxibustion treatment and after two months of treatment(P<0.05).After heat-sensitive moxibustion treatment,there were significant differences in QOL score,IPSS score,RUV and Qmax between heat-sensitive moxibustion group B and heat-sensitive moxibustion group A(P<0.05).There was no significant difference in QOL score,IPSS score,RUV and Qmax between the heat-sensitive moxibustion group A and the heat-sensitive moxibustion group B after heat-sensitive moxibustion and the two-month follow-up after heatsensitive moxibustion(P>0.05).4.Comparison of effective rate: The effective rate of heatsensitive moxibustion in group A was 64.5%,the rate of cure was 45.1%,the follow-up efficiency after 2 months was 67.74%,the rate of cure was 48.3%;the efficiency of heat-sensitive moxibustion group B was 95.7%,the cure rate was 73.9%,and the follow-up efficiency was 91.3% after 2 months,and the cure rate was 69.6%.There was significant difference in the effective rate between the heat-sensitive moxibustion group A and the heat-sensitive moxibustion group B(P<0.05).Conclusion:1.Heat-sensitive moxibustion can significantly improve the clinical symptoms of benign prostatic hyperplasia.2.The Efficacy of moxibustion is closely related to the intensity of moxibustion when it is terms to heat-sensitive moxibustion treats benign prostatic hyperplasia. |