| Objective:To analyze the distribution of risk factors in patients with acute stroke complicated with deep vein thrombosis of lower limbs,and to provide clinical data for evaluating the risk of acute stroke complicated with deep vein thrombosis of lower limbs and taking reasonable and effective preventive measures and treatment.Methods:A total of 3,998 patients admitted to the department of neurology of ningxia medical university general hospital from January 2015 to December 2018 and diagnosed with acute stroke were selected,among which 175 patients complicated with LDVT were studied.Baseline data,risk factors,preventive measures,treatment,prognosis and other clinical data were collected according to inclusion and exclusion criteria.All data were analyzed using SPSS 22.0 statistical software:Measurement data are expressed in(Mean ± standard deviation),Counting data are expressed by frequency and composition ratio.T-test was used for the comparison of normal distribution data between two groups,and X2 test was used for the comparison of counting data between two groups.P<0.05 had statistical significance.Results:1.The incidence of LDVT in stroke patients was 4.38%.2.The majority of patients with LDVT were old age(61-70 years old),hypertension(72.57%)and smoking(29.14%).3.The composition ratio of different types of stroke atrial fibrillation in patients with LDVT was significantly different(P<0.05).4.Among the patients with LDVT,75.43% had muscle strength less than or equal to grade 2,and 37.72% were in lethargy and coma.5.Among the patients with LDVT,41(23.43%)underwent color Doppler ultrasonograph-y of the lower extremities to detect the clinical symptoms associated with LDVT.The most common clinical manifestation was limb swelling(8.0%).The most common venous involvem-ent site was the leg muscular venous plexus(46.43%).The most common LDVT type was peripheral type(64.29%).6.Most stroke patients were found with LDVT 8-14 days after admission,and LDVT was found for different stroke types with statistical differences(P<0.05).The ischemia group was found with 8-14 days,while the hemorrhage group was found with 15-21 days.7.In LDVT patients,WBC,neutrophil relative value,TG and D-dimer of different stroke types were significantly different(P<0.05),while fasting blood glucose,hemoglobin,albumin,TCHO,LDL,HDL,TT,PT,fibrinogen,APTT and INR were not significantly different(P>0.05).8.Among the patients with LDVT,the incidence of pulmonary infection was the highest(50.29%),and the incidence of PTE of different stroke types was significantly different(P<0.05),while the incidence of pulmonary infection and urinary tract infection was not significantly different(P>0.05).Among stroke patients,157(3.93%)took LDVT-related preventive measures,and the incidence of LDVT decreased after taking preventive measures.10.After anticoagulation therapy for LDVT patients,deep vein thrombosis of lower limbs disappeared in 29 patients and pulmonary artery thrombosis disappeared in 17 patients.Conclusion :1.The risk of LDVT in stroke patients is the highest among the elderly(61-70 years old),hypertension and smoking.2.The most common clinical symptom of patients with LDVT is limb swelling,the most common venous involved part is intramuscular venous plexus of the lower leg,and the most common type of LDVT is peripheral type.3.In this study,reasonable and effective preventive measures can reduce the incidence of LDVT after stroke.4.For stroke patients with clinical symptoms of LDVT and/or D-dimer greater than0.5mg/L after admission,color doppler ultrasound of lower limbs should be improved in time for early diagnosis and treatment,To prevent the occurrence of pulmonary embolism. |
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