High Risk Factors Of Deep Venous Thrombosis In Patients With Endometrial Cancer During Perioperative Period

Objective:To investigate the related factors of deep venous thrombosis in patients with endometrial cancer during perioperative period.Methods:A retrospective analysis of 516 cases of endometrial cancer diagnosed in the First Hospital of Lanzhou University from February 1,2013 to January 31,2019,41 patients with deep venous thrombosis of lower extremity were selected as experimental group and 41 patients in the same period with endometrial carcinoma as control group.The two groups were compared in general,preoperative laboratory examination,intraoperative status and postoperative clinical pathology.Results:Univariate analysis showed hypertension(P=0.012),diabetes(P=0.018),body mass index(BMI,P=0.028),used to take estrogen and progesterone drugs(P=0.040)?platelets greater than 300×10~9/L(P=0.018),cholesterol(P=0.000),D-dimer(P=0.023),operative time(P=0.025),intraoperative bleeding(P=0.029),lymph node metastasis(P=0.012),tumor differentiation(P=0.018),and tumor Staging(P=0.002)showed statistically significant differences between the thrombosis group and the control group in perioperative endometrial cancer patients.Logistic regression analysis showed that patients with hypertension,patients with BMI>27 kg/m~2,used to take estrogen and progesterone drugs,platelet count>300×10~9/L,increased operative time,increased bleeding,increased lymph node metastasis,low tumor differentiation,tumor FIGO staging is the uterus High risk factors for deep venous thrombosis in patients with endometrial cancer.Conclusions:In endometrial cancer patients with hypertension,BMI>27 kg/m~2,used to take estrogen and progesterone drugs,platelet count>300 10~9/L,increased operative time,increased intraoperative blood loss,lymph node metastasis,low degree of tumor differentiation and late FIGO stage,it is necessary to control the above risk factors during the perioperative period and adopt other methods to prevent lower limb deep vein thrombosis.