Correlation Between Coronary Artery Stenosis And Risk Factors In Elderly Patients With Coronary Heart Disease

Objective:To explore the correlation between the severity of coronary artery stenosis and risk factors in elderly patients with coronary heart disease,and to provide a basis for the clinical application of serological indicators to predict the degree of coronary artery stenosis.Methods:A total of 163 inpatients over 60 years of age who were transferred to the Department of Cardiology for coronary heart disease in the general medical department from October 2017 to December 2019 in the first affiliated hospital of china medical university were selected as the research object,including 93 males and 70 females.All patients were diagnosed with coronary heart disease for the first time with diagnostic coronary angiography and had complete clinical data.The basic conditions and laboratory examination results of the patients were queried.According to the diagnosis and management of the 2019 European Society of Cardiology,chronic coronary syndrome"Guide"^[1],combined with coronary angiography results,patients were divided into two groups of coronary heart disease and control group,including 113 cases of coronary heart disease group and 50 cases of control group.The severity of coronary artery stenosis was graded by modified Gensini score,and patients with coronary heart disease were divided into mild stenosis group?1-7 points?,moderate stenosis group?8-14points?and severe stenosis group?>14 Points?Three groups.Use spss22.0 software for statistical analysis,using:t test,chi-square test,single factor analysis,multi-factor analysis,difference analysis,Pearson correlation analysis,with a=0.05 as the test level,P<0.05 difference is statistically significant significance.Results:1.After comparing the data between the two groups of coronary heart disease and the control group,it is concluded that:age,gender,history of diabetes,glycated hemoglobin,systolic blood pressure,homocysteine,lipoprotein a,high-density lipoprotein cholesterol and low-density lipoprotein Cholesterol and other indicators were statistically significant?P<0.05?.There was no significant difference in the history of hypertension,diastolic blood pressure,thyroid stimulating hormone,uric acid,r-glutamyl transferase?P>0.05?;2.different coronary The comparison between the number of arterial stenosis results:age,male,history of diabetes,glycated hemoglobin,systolic blood pressure,homocysteine,lipoprotein a,high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels in different coronary artery lesions The difference between the counts was statistically significant?P<0.05?;3.Correlation analysis of coronary heart disease risk factors and coronary artery stenosis showed:age,systolic blood pressure,homocysteine,lipoprotein a and low density lipoprotein cholesterol and Coronary artery stenosis was positively correlated?r>0,P<0.05?,high-density lipoprotein cholesterol was negatively correlated with coronary artery stenosis?r=-0.287,P<0.01?;4.Correlation analysis of different coronary artery stenosis and coronary heart disease risk factors suggests that severe coronary stenosis is related to age,Hcy and Lp?a??P<0.05?,mild coronary stenosis is associated with systolic blood pressure and LDL-C?P<0.05?.Conclusions:The history of men and diabetes accounts for a large proportion of the coronary heart disease group and the multi-vessel coronary stenosis group.The age,systolic blood pressure,glycated hemoglobin,Hcy,Lp?a?and LDL-C levels of the coronary heart disease group and the multi-vessel disease group increased significantly High,HDL-C levels decreased;coronary stenosis was positively correlated with age,systolic blood pressure,Hcy,Lp?a?,LDL-C,and negatively correlated with HDL-C,and severe coronary stenosis was associated with age,Hcy,and Lp?a?,mild coronary stenosis is related to systolic blood pressure and LDL-C.