The Value Of Multimodal Ultrasound In The Diagnosis Of Prostate Cancer

OBJECTIVE: To explore the diagnostic value of multimodal ultrasound,namely transrectal two-dimensional ultrasound,shear wave elastography,and contrast-enhanced ultrasound,in prostate cancer.Methods: From December 2017 to December 2019,146 patients with suspected prostate cancer in our outpatient and inpatient hospitals underwent transluminal ultrasound-guided prostate biopsy,and all were performed with transluminal two-dimensional ultrasound,shear wave elastography,and Contrast-enhanced ultrasound,with pathological results as the gold standard,obtains the sensitivity and specificity of transrectal two-dimensional ultrasound,shear wave elastic imaging,contrast-enhanced ultrasound,and the sensitivity and specificity of combined diagnosis,and uses rank correlation to analyze the elasticity of prostate lesions Correlation between Young's modulus value,serum PSA,age and Gleason score of pathological results of prostate cancer.Results: The accuracy of multimodal ultrasound in the diagnosis of prostate cancer was 88.4%,and the distribution of sensitivity,specificity,positive predictive value,and negative predictive value were 85.7%,97.1%,99.0%,and 67.3%.Compared with single-mode ultrasound diagnostic efficacy,the difference was statistically significant(P <0.05).Shear wave elastography can detect 14 cases of prostate cancer missed by contrast-enhanced ultrasound.Contrast-enhanced ultrasound could also detect 4 cases of prostate cancer that were missed by shear wave elastography.Multimodal ultrasound was able to detect 12 cases of prostate cancer misdiagnosed by shear wave elastography.Shear wave Young's modulus value and serum PSA value were positively correlated with the Gleason score of prostate cancer pathology,and there was no correlation between age and Gleason score of prostate cancer pathology.Conclusion: Multimodality ultrasound is a promising imaging method in the diagnosis and differential diagnosis of prostate cancer,and it is worthy of clinical promotion.Shear wave Young's modulus value and serum PSA value can predict the Gleason score of prostate cancer pathology to some extent.