Observation On The Clinical Effect Of Tangwangmingshi Prescription In The Treatment Of Non-proliferative Diabetic Retinopathy With Qi-yin Deficiency And Blood Stasis Blocking Syndrome

Objective To evaluate the results of two different treatment methods through the intervention of tangwangmingshi prescription in patients with non-proliferative diabetic retinopathy.Methods 1.Sixty-two patients with type 2 diabetic non-proliferative retinopathy who met the inclusion criteria were randomly divided into observation group and control group.2.The two groups are lifestyle intervention and routine western medicine hypoglycemic treatment,control group patients with hydroxyl benzene sulfonic acid calcium capsules orally(0.5 g/time,3 times/day),the observation group patients with hydroxyl benzene sulfonic acid calcium capsules(0.5g/time,3 times/day)and tangwangmingshi prescription(the party unified by the Inner Mongolia autonomous region people’s hospital of TCM pharmacy preparation,particle form,1 g/time,2 times/day,half an hour after the meal warm boiling water take)oral;12 weeks of treatment.3.Observe and record the changes of visual acuity,optical coherence tomography(OCT),TCM syndrome score,hemorheology,blood lipid,fasting blood glucose and other indicators before and after treatment in the two groups of patients,and evaluate the therapeutic effect of TCM syndrome,vision level and therapeutic effect of fundus lesions,and apply statistical correlation method for analysis.Results 1.Curative effect of TCM syndromes: the total effective rate was86.67% in the observation group and 53.33% in the control group.After comparison,the observation group was higher than the control group,with significant difference(P<0.01).2.Visual and fundus lesions: visual acuity: the total effective rate was83.33% in the observation group and 63.33% in the control group,which was higher in the observation group than in the control group,with significant difference(P<0.01).The therapeutic effect of fundus lesions was 83.33% in the observation group and 66.67% in the control group,which was higher than that in the control group(P<0.05).3.Hemorheology: the hemorheology level of patients in both groups decreased after treatment compared with that before treatment(P<0.05),and the observation group was better than the control group(P<0.05).4.Fasting blood glucose,glycosylated hemoglobin and blood lipid: there were no significant changes in fasting blood glucose,glycosylated hemoglobin and blood lipid in the two groups before and after treatment,with no significant difference(P>0.05),indicating stable control before and after treatment;5.During the observation period,patients in the two groups showed stable vital signs,normal ecg,blood,urine routine and liver and kidney functions,and no obvious adverse reactions occurred after taking the drug,showing good safety.Conclusion 1.In improving the TCM syndromes,vision,fundus lesions and hemorheology of patients with non-proliferative diabetic retinopathy,the efficacy of Tangwangmingshi prescription group was better than that of simple calcium hydroxybenzosulfonate capsule group;2.In delaying and controlling the development of non-proliferative diabetic retinopathy,Tangwangmingshi prescription group was better than that of simple calcium hydroxybenzosulfonate capsule group;3.Tangwangmingshi prescription for non-proliferative diabetic retinopathy was positive and safe and had clinical value.