The Clinical Study On Proliferative Diabetic Retinopathy With Chinese Traditional Medicine -Damingyin

Purposes: To evaluate the efficacy of the DA MING YIN for treatment of proliferative diabetic retinopathy(PDR),and to explore the mechanism of the DA MING YIN with functions of replenishing qi and producing yin, activating blood circulation to dissipate blood stasis.Methods: 32 NIDDM patients with PDR and eyeground change were randomly assigned (16:16) to the treatment group (DA MING YIN) and the controlled group (DOXIUM). Examination of vision, eyeshot and Color Doppler flow imaging (CDFI); photography of eyeground, fundus fluorescein angiography before treatment and after one month were used to evaluate the effects of DA MING YIN impersonally.Results: (1) The percentage of the total effective cases of the treatment group was 65.63%, and the controlled group was 46.88%,P<0.05,so DA MING YIN is superior to DOXIUM.(2)Vision: Comparison in the treatment group and the controlled group has statistical significance (P<0.05) by T.The vision of two groups both have some statistical significance before treatment and after clinical therapy.(3) The treatment group, whose percentage of the total effective cases is 71.88%, is superior to the controlled group, whose is 56.67%, in eyeground examination and fundus fluorescein angiography. Comparisons between the groups have statistical significance (P<0.05).(4)Eyeshot: The treatment group has statistical significance (P<0.05); the controlled group has statistical significance (P>0.05); contrasts between two groups after treatment have no statistical significance (P>0.05).(5)Retina flow of two groups both have some improvement through clinical therapy; comparisons in the treatment group have statistical significance in PSV,RI and EDV (P<0.05) before treatment and after clinical therapy. Contrasts in the controlled group' RI have statistical significance (P<0.05), but in PSV and EDV have no (P>0.05). Contrasts between two groups after treatment have statistical significance in PSV and EDV (P<0.05), but in RI have no (P>0.05).Conclusion: Curative effect of Chinese traditional medicine DA MING YIN in proliferative diabetic retinopathy (PDR) is significant, and superior to DOXIUM.