| ObjectivesTo explore the efficacy of traditional Chinese medicine smearing combined with massage on treating the patients with psoriasis vulgaris with damp-heat syndrome and observing the effect on patients’ clinical symptoms,pruritus degree and quality of life.Methods1.Study design: A random,controlled trial was used in this study.80 patients with psoriasis vulgaris with damp-heat syndrome who met the criteria for inclusion and exclusion in a hospital in Chengdu were selected as subjects.According to the random number table,the subjects were randomly divided into interventional group and control group,40 cases in each group.2.Interventions:Based on the treatment for psoriasis vulgaris with damp-heat syndrome and usual care.On this basis,the control group was given traditional Chinese medicine smearing method,while the experimental group was treated with massage on the basis of traditional Chinese medicine smearing method.3.Data collection:(1)General information such as the sex,age,education level,course of disease,and living habits was collected on the day of admission.(2)Efficacy index: Psoriasis area and severity index(PASI)score,PASI individual score(the skin lesion area,erythema,infiltration,scale),pruritus score,Dermatology life quality index(DLQI)score were observed,evaluated and recorded on the day of admission and at the end of three treatment courses.4.Data processing: Epidata software was used for data double input,and SPSS20.0 was used for data statistics analysis.Two-sided test was used in statistical analysis with a statistical significance of α=0.05.Result1.A total of 80 subjects were included in this study,every 39 cases in experimental group and control group.During the entire experiment,1 case wasabsent from the experimental group and 1 case leaved form the control group.Finally,78 cases were included in the study,every 39 cases in both groups.2.Comparison of baseline data:(1)comparison of general data: The results shows that there are no significant differences in age,gender,degree of education,course of disease,and living habits between the two groups(P>0.05).(2)Comparison of efficacy indexes between the two groups before intervention: The results shows that PASI individual score(the skin lesion area,erythema,infiltration,scale),PASI score,pruritus score,Dermatology life quality index(DLQI)score between the two groups are not statistically significant(P>0.05).3.Efficacy comparison within same group before and after intervention: The results shows that after the intervention,PASI individual score(the skin lesion area,erythema,infiltration,scale),PASI score,pruritus score,and Dermatology life quality index(DLQI)score of the two groups are lower than those before the intervention,and the differences are statistically significant(P<0.05).4.Comparison of efficacy indexes between the two groups after intervention: The results shows that after the intervention,erythema,infiltration and scale score,PASI score,pruritus score,and Dermatology life quality index(DLQI)score of the experimental group are lower than those of the control group,and they are statistically significant(P<0.05).There are no significant differences in the score of skin lesion area between the two groups(P>0.05).5.Comparison of clinical effects between the two groups: The total effective rates of the experimental group and the control group are 87.18% and 74.36%,respectively,and the total effective rates of the experimental group are higher than the control group,and they are statistically significant(P<0.05).Conclusion1.Both traditional Chinese medicine smearing and traditional Chinese medicine smearing combined with massage can improve the clinical symptoms,pruritus degree and quality of life of patients with psoriasis vulgaris with damp-heat syndrome.2.The traditional Chinese medicine smearing combined with massage is betterthan traditional Chinese medicine smearing in the skin lesion severity score(erythema,infiltration,scale)score,Psoriasis area and severity index(PASI)score,pruritus score,and Dermatology life quality index(DLQI)score,but it can’t be proved yet that the efficacy is different between the two methods on improving the score of skin lesion area. |