Construction And Verification Of Health Education Mode Of Integrated Traditional Chinese And Western Medicine In Menopausal Syndrome

Objective:Establish a health education model of integrated traditional Chinese and western medicine for menopausal syndrome.and verify the effectiveness and safety of the health education model of integrated traditional Chinese and western medicine for menopausal syndrome through small sample clinical studies,in order to provide a comprehensive and specific health education new model of integrated traditional Chinese and western medicine for menopausal syndrome and improve patients'quality of life.Method:Chinese databases such as CNKI,Wan Fang Data,VIP,China Biology Medicine disc,etc were searched,and the literatures on menopausal syndrome related risk factors that met the inclusion criteria were statistically analyzed,and the risk factors that could be adjusted and intervened were obtained.At the same time,all kinds of health education materials of menopausal syndrome were retrieved from CNKI.The literatures were statistically analyzed and summarized to obtain comprehensive and specific health education materials of menopause syndrome.Referenced to the relevant health care guidelines for menopausal syndrome,combined with the relevant risk factors and the results of health education data surveys,integrated health care therapies of traditional Chinese medicine,constructed a health education model of integrated traditional Chinese and western medicine for menopausal syndrome.and conducted a small sample clinical verification.A total of 72 subjects who met the diagnostic criteria for menopausal syndrome in the gynecology department of the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from January 2019to November 2019 were included.The subjects were randomly divided into a traditional Chinese and western medicine group and a western medicine group according to random numbers,with 36 patients in each group.The group of traditional Chinese and Western Medicine carried out health education of combination of traditional Chinese and western medicine;the group of western Medicine carried out health education of western medicine guide.The course of treatment was 8 weeks,and the follow-up was 4 weeks.The form of health education included outpatient visits,distribution of brochures,telephone,We Chat,etc.The follow-up time was 0 weeks,2 weeks,4 weeks,6 weeks,8 weeks and 4 weeks after the end of treatment.Menopause-Specific Quality of Life,TCM Syndrome Score,FSH,LH,E₂,blood lipids,and blood glucose were used as efficacy evaluation indicators.Compared the differences of therapeutic effect indexes at each follow-up time point,and evaluated the compliance and safety of the two groups.The experimental data were statistically analyzed using SPSS 17.0.Results:1.The improvement of MENQOL scale:The scores of MENQOL total scale,vasomotor dimension score,mental state dimension score,physiological state dimension score,and sexual life dimension score at all time points in the two groups after treatment were all reduced compared with 0 weeks?P<0.05?.The improvement of MENQOL total score,vasomotor dimension score,mental state dimension score,and physiological state dimension score of the integrated Chinese and western medicine group at all time points after treatment were better than those of the western medicine group?P<0.05?.At 8 weeks and 4 weeks after the end of the treatment,the improvement of the sexual life dimension score of the integrated Chinese and western medicine group was better than that of the western medicine group?P<0.05?.2.Improvement of TCM Syndrome Score:After treatment,the total scores of TCM syndromes and the scores of symptoms of kidney yin deficiency such as five upset fever,dry mouth and dry throat were lower than those before treatment?P<0.05?.The improvement of the total scores of TCM syndromes and the scores of symptoms of kidney yin deficiency such as five upset fever,dry mouth and dry throat at all time points after treatment were better than those of western medicine group?P<0.05?.The scores of typical symptoms of kidney yang deficiency such as chilly limbs and frequent urination at night at all time points after treatment in the group of integrated traditional Chinese and western medicine were lower than those in week 0?P<0.05?.The scores of typical symptoms of kidney yang deficiency such as chilly limbs and frequent urination at night in the group of western medicine were not significantly different between week 8 and week 0?P>0.05?.And the scores of 4 weeks after the end of the treatment were lower than that in week 0?P<0.05?.The scores of typical symptoms of kidney yang deficiency such as chilling limbs coldness,night frequency urination at all time points after treatment in the integrated Chinese and western medicine group were lower than those in the western medicine group,but there was no significant difference between the groups?P>0.05?.3.Post-treatment effect comparison:compared with that at the end of 8 weeks,there was no significant increase in the total score of MENQOL scale and TCM syndrome score in the two groups at 4 weeks after the end of the treatment.The scores in the integrated Chinese and western medicine group were lower than those in the western medicine group at 4 weeks after the end of the treatment?P<0.05?.4.Improvement of biochemical indicators:There were no statistically significant differences in blood glucose and lipids between the two groups before and after treatment?P>0.05?.After treatment,the levels of FSH and LH in both groups decreased,and the level of E₂increased.However,there was no statistically significant difference in FSH and LH levels between the two groups before and after treatment?P>0.05?.There was a statistically significant difference in the E₂level of the integrated Chinese and western medicine group?P<0.05?.And there was no statistically significant difference in the E₂level of western medicine group?P>0.05?.5.Compliance and safety evaluation:The dropout rate of the subjects in this study was 9.7%?7/72?,of which the dropout rate of the integrated Chinese and western medicine group was8.3%?3/36?,and the dropout rate of the western medicine group was 11.1%?4/36?,there was no significant difference in the dropout rate between the two groups?P>0.05?.Among the 72subjects,only 1 case in the integrated traditional Chinese and western medicine group had adverse reactions,which was manifested as dizziness after the Ba Duan Jin exercises involving the bow head movement.Ask for medical history,She had a history of cervical spine for years.Let her stop the exercise of Ba Duan Jin.And after the appropriate rest the symptom relieved.Conclusions:The health education model of integrated traditional Chinese and western medicine for menopausal syndrome is effective and has good compliance.It is worthy of further clinical promotion.It can significantly improve the quality of life and TCM syndromes of patients with menopausal syndrome and has a good post-treatment effect.And It's effect is better than the health education model of western medicine.Compared with the health education mode of western medicine,the health education mode of integrated traditional Chinese and western medicine has a greater advantage in improving vasomotor symptoms,mental state,physiological state and sexual life related symptoms;in TCM syndrome,it has a greater advantage in improving kidney yin deficiency related symptoms.The health education model of integrated traditional Chinese and western medicine has an up-regulation effect on E₂levels in patients with menopausal syndrome.Whether this is related to its effect mechanism of action needs further study.