Effects Of Health Qigong Baduanjin On Event Related Potential P300 And N200 In Elderly Patients With Mild Cognitive Impairment

Purpose : To explore the difference of Event Related Potential(ERP)before and after Health Qigong Exercise in Mild Cognitive Impairment(MCI)Patients by using EEG,and to explore the impact of physical and mental exercises(Health Qigong)on cognitive function and activity of cerebral cortex of cognitive dysfunction.Methods: Thirty subjects with mild cognitive impairment(MCI)aged 60-70 years were selected by AD8,MMSE and MoCA and randomly divided into experimental group and control group of 15 people.Finally,12 subjects were completed,6 subjects(3 male and 3 female)of the experimental group and 6 subjects(3 male and 3 female)of the control group.The experimental group was given Health Qigong exercise for a period of 4 months while the control group without any intervention.The experimenter separately tested the response time and accuracy of behavioral data of the experimental group and the control group before and after exercise and the event-related potentials P300 and N200.The results were analyzed by paired samples within groups and independent samples among groups with t test(P<0.05 for statistical differences).Result:(1)After four months of experiment,the amplitude of central electrode C1 and C2 and parietal lobe CPz of Go-P300 significantly increased(P<0.05).There was no statistical significance(p>0.05)in latency of Go-P300 between the two groups after four mouths experiment.(2)After four months of experiment,the amplitude of NoGo-P300 central electrode C1,Cz,C2 and parietal electrode CPz point was increased,and statistically significant(P<0.05)compared with before experiment in the experimental group.After four months of experiment,the amplitude of the control group and the experimental group compared with the C2 amplitude decreased,and with statistical significance(P<0.05).There was no statistical significance(p>0.05)in latency of NoGoP300 between the two groups after four mouths experiment.(3)Through the four-month experiment,the amplitude of NoGo-N200 central electrode Cz point,parietal electrode CPz point of experimental group increased significantly(P<0.05).There was no statistical significance(p>0.05)in latency of NoGo-P300 between the two groups after four mouths experiment.In addition,the Go-N200 amplitude,Go-N200 latency,actionresponse time or correct rate were no statistically significant across the four months of the experiment(p>0.05).Conclusions:(1)Four months of Health Qigong can boost the mobilization of attentional resources of MCI and the renewal of the working memory environment in MCI patients.(2)Four months of Health Qigong can improve the ability of MCI patients to assess and test the response.(3)Four months of Health Qigong exercise can improve the ability of MCI patients to inhibit motor response.