Clinical Observation Of Xingqi Qingjiang Decoction In Treating Non-erosive Reflux Disease With Stagnation Of Heat In The Liver And Stomach

Objective:By using Gerd Q scale and TCM syndrome scale,this paper studied the clinical efficacy of xingqi qingjiang recipe in the treatment of non-erosive reflux disease with liver and stomach heat retention syndrome.Methods:From December 2016 to December 2018,a total of 72 patients who met the diagnostic criteria of non-erosive reflux disease with liver and stomach heat retention syndrome were studied in the tutor clinic of dongzhimen hospital of Beijing university of traditional Chinese medicine,including 12 cases of shedding and 60 cases of effective enrollment.According to the random number distribution method,the patients were divided into experimental group(30 cases)and control group(30 cases).The experimental group was given xingqi qingjiang recipe(taking method:twice a day,respectively half an hour before breakfast and two hours after dinner each one bag),the control group was given pantoprazole sodium enteric-coated capsules(taking method:once a day,one granule once a time,oral administration on an empty stomach half an hour before breakfast).The duration of drug treatment in this study was 8 weeks;record before,8 weeks after the experimental group and control group of GerdQ scale,TCM syndrome scale score,to enter data from Excel system to establish the database,use SPSS25.0 statistical software to analyze data,so as to evaluate the clinical efficacy of xingqi qingjiang recipe in the treatment of non-erosive reflux disease with liver and stomach heat retention syndrome.Results:1 General data analysis and comparisonThere was no significant difference in the results of gender,age and disease course,and the two groups were comparable.2 Gerd Q scale analysis and comparison2.1 Gerd Q scale scores before and 8 weeks after treatment in the experimental group and the control group were compared in each group,and the P values were all less than 0.01,with statistically significant differences,indicating that both the experimental group and the control group were effective in the treatment of non-erosive reflux disease with liver and stomach heat retention syndrome.2.2 Comparison of Gerd Q scores between the experimental group and the control group after 8 weeks of treatment,P=0.026(P<0.05),the difference was statistically significant,indicating that the treatment effect of the experimental group was better than that of the control group.3 TCM syndrome rating scale analysis and comparison3.1 Comparison of TCM syndrome scores between the experimental group and the control group before and after treatment for 8 weeks showed that P value was less than 0.01,indicating that both the experimental group and the control group could effectively improve TCM symptoms of patients with liver and stomach heat retention syndrome of non-erosive reflux disease.3.2 Comparison of TCM syndrome evaluation groups between the experimental group and the control group after 8 weeks of treatment,P<0.01,the difference was statistically significant,indicating that the experimental group was better than the control group in improving the efficacy of TCM symptoms.3.3 There were statistically significant differences between the experimental group and the control group in the single symptom of improving symptoms,such as acid regurgitation(P=0.016),noisy(P=0.002),bilateral pressure swelling(P=0.04),upset(P<0.01),bitter mouth(P<0.01),and secreted stool(P<0.01).There was no significant difference in other symptoms.4 Analysis and comparison of TCM syndrome efficacy and clinical efficiency4.1 In the experimental group,7 patients were cured,16 were obviously effective,5 were effective,and 2 were ineffective.The clinical effective rate was 93.33%.4.2 In the control group,3 patients were cured,1 was obviously effective,23 were effective,3 were ineffective,and the clinical effective rate was 90%.4.3 Comparison of clinical effective rate between the experimental group and the control group(P=1.00),indicating that both the experimental group and the control group were effective in the treatment of non-erosive reflux disease,but there was no significant difference,5 No adverse reactions occurred in the two groups during the treatment,indicating that the experimental group and the control group had better drug safety.Conclusion:Through analysis and comparison in this topic 60 cases of general information,Gerd Q scale,and TCM syndrome scale data,we can get that the experimental group xingqi qingjiang recipe could improve the symptoms of non-erosive reflux disease patients with liver and stomach heat retention syndrome,no adverse reaction,It shows that xingqi qingjiang recipe is effective in treating non-erosive reflux disease.