Professor Guo Zhiqiang's Clinical Observation On The Treatment Of Polycystic Ovary Syndrome With The Method Of Invigorating The Kidney And Regulating The Week

Objective:Polycystic ovary syndrome is a common clinical disease with clinical manifestations mainly of endocrine disorders and metabolic disorders.The incidence of the disease is gradually increasing.The incidence of this disease is mainly of women of childbearing age.The etiology of this disease is diverse,and it is related to genetic susceptibility,lifestyle,environmental factors,inflammatory stimuli,etc.The pathogenesis is not clear.In recent years,more and more studies have found that AMH is closely related to polycystic ovary syndrome,which can indicate the severity of PCOS,so it can be used as an indicator of the efficacy of PCOS.Chinese medicine believes that the pathogenesis of this disease is based on kidney deficiency.This study collects patients with polycystic ovary syndrome treated with GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle,and observed changes in BMI,gonadal hormone hormones,AMH,glucose metabolism,lipid metabolism,ovarian volume,TCM symptoms,acne,hairiness and other indicators before and after treatment.Then analysising data according to statistical results,preliminary discussion of the comprehensive efficacy of GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle in the treatment of polycystic ovary syndrome.To provide more methods for clinical treatment of polycystic ovary syndrome,accumulate experience of flexible changes in prescription medication,and provide new ideas.Methods:According to the diagnostic criteria of polycystic ovary syndrome,draw up the inclusion criteria,exclusion criteria,and shedding criteria of this study.We select 36 patients with polycystic ovary syndrome who met the diagnostic criteria,treat them with GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle in three menstrual cycles.Then we use the method of prospective study,to observe BMI,gonadal hormone,AMH,glucose metabolism,lipid metabolism,ovarian volume,TCM symptoms,acne,hairiness and other indicators before and after treatment.Then we statistically evaluate the improvement of observation indicators,and record adverse reactions.The ultimate purpose is to summarize the clinical efficacy of GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle in treating polycystic ovary syndrome.Results:1.The average age of 36 patients with PCOS was 29.39 years,of which 25-30 years were the most,with 21(52.8%);followed by 31-35 years,with 11(30.5%);among them,the majority of patients are 25-32 years old,with 30(83.3%),mainly females of childbearing age.2.The average BMI value of 36 PCOS patients was 25.68 kg/m2;16 patients(44.5%)in?23.9kg/m2;13 patients(36.1%)in 24-30kg/m2;7 atients(19.4%)in>30kg/m2.3.The results of this study show that the total effective rate of GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle treats polycystic ovary syndrome was 97.2%.4.The BMI level of PCOS patients decreased after treatment,P<0.01,the difference was statistically significant.LH,T,and E2 decreased,P<0.01,the difference was statistically significant,and it also has a reducing effect on the ratio of LH/FSH,P<0.05,the difference was statistically significant,FSH and PRL was not significantly changed.The serum AMH level decreased,P<0.01,the difference was statistically significant.The glucose metabolism indexes FPG,FIN,and HOMA-IR decreased,P<0.01,and the difference was statistically significant.Lipid metabolism level HDL was higher than before treatment,LDL was lower than before treatment,P<0.01,the difference was statistically significant,TG and TC were not significantly improved,and the difference before and after treatment was not statistically significant.The average ovarian volume decreased significantly after treatment,P<0.01,the difference was statistically significant.TCM syndrome scores decreased,P<0.01,and the difference was statistically significant.The total effective rate of TCM syndrome scores was 97.2%.The condition of acne and hairiness was significantly improved,P<0.01,and the difference was statistically significant.Conclusions:GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle treats polycystic ovary syndrome,it can significantly reduce BMI value in patients with PCOS,improve gonadal hormone levels,reduce serum AMH value,improve glucose metabolism and lipid metabolism in patients,and it also can reduce the increased ovarian volume,improve the condition of polycystic ovarian changes in patients with PCOS,improve the symptoms of TCM,acne and hairiness.GUO Zhiqiang's method of tonifying kidney and regulating menstrual cycle can restore ovulation and menstruation while alleviate clinical symptoms in patients,and have no obvious adverse reactions,it is safe and reliable,and worthy of clinical promotion.