Sleep Regulation System Based On Non-invasive Physical Intervention

With the development of the times,the huge life pressure has caused more and more people to be troubled by the same problem-sleep disorder,which not only affects people’s physical state but also may directly lead to psychological problems.Therefore,it is very meaningful to use some effective ways to regulate sleep.Non-invasive physical interventions,such as visual stimulation,olfactory stimulation,auditory stimulation,etc.,are used by a large number of researchers in sleep regulation research because of their non-invasiveness to the human body.At present,in the above-mentioned studies,most researchers need to use multiple devices to collect sleep data and apply non-invasive physical intervention to the subjects,which leads to complicated operation of sleep regulation experiments.Compared with multiple devices,a system can perform acquisition and control at the same time,which can facilitate researchers to conduct experiments.Therefore,this thesis independently designed and produced a sleep regulation system integrating EEG acquisition and non-invasive physical intervention.The system includes hardware and software: the hardware part is mainly composed of an EEG acquisition circuit and a physical intervention peripheral circuit,which can realize the acquisition of sleep data,and can apply non-invasive vibration stimulation and electrical stimulation to regulate the sleep state;the software part can realize the interaction with hardware and real-time display,storage and analysis of EEG data.At the same time,the hardware in the above system is tested for gain,noise,common mode rejection ratio,and electrical stimulation output error.The test results verify the feasibility of the hardware circuit design.This thesis also uses the system to carry out sleep acquisition comparison experiments and sleep regulation experiments.Among them,a total of 40 nights of sleep acquisition comparison experiments for 15 subjects were completed.By comparing the sleep data acquisition results of the system and PSG equipment,it was verified that the system can collecte the whole night’s sleep data,and the collected data could be used for sleep staging;15 subjects completed a30-night vibration stimulation regulation experiment,and the experimental results found that there was a significant difference in the subjects falling asleep on a normal night and a vibration night（P=0.014）.It shows that the vibration stimulation of the system has a significant effect on shortening the time for the subjects to fall asleep,which is shortened by about 8 minutes;15 subjects have completed a 30-night electrical stimulation regulation experiment,and the experimental results show that the total sleep time of the subjects in normal nights and electrical stimulation nights is significantly different（P=0.038）,indicating that the electrical stimulation of the system significantly reduced the total sleep time of the subjects by about 20 min.Moreover,the increase of sleep arousal in the night of electrical stimulation had a negative impact on the subjects’ psychomotor vigilance.After receiving electrical stimulation,the subjects’ PVT test scores decreased by about 5.45%,which was significantly different from the scores before electrical stimulation（P=0.027）.The above results validate the effectiveness and reliability of the system described in this thesis,indicating that the system can be used in subsequent sleep regulation studies.