Contrastive Analysis Of EEG Between People With Accommodative Dysfunctions And Normal Under The Flipper Stimulation

Purpose: With the rapid development of informatization,electronic products are used in all aspects of work,study,and life,and the visual load continues to increase.At the same time,people’s health levels continue to improve.In addition,the subspecialty of ophthalmology is admitted and gradually developed.The incidence of accommodative dysfunction and the rate of outpatients are on the rise.This kind of functional eye disease has obvious symptoms,which seriously affects people’s quality of life and reduces learning and work efficiency.However,due to the accommodative dysfunctions with no ocular organic diseases,the diagnosis is mainly based on the patient’s clinical symptoms and visual function examination results.The subjectivity is strong,and the diagnosis,training and treatment require clinical subspecialists to invest a lot of time and energy.At present,this kind of patients has not been fully treated.Therefore,in order to further understand this disease,we have explored the characteristics of the disease from the perspective of EEG.The two groups of people with accommodative dysfunctions and normal controls were given the flipper stimulation,and the EEG of the two groups were collected at the same time.The wavelet time-frequency analysis method was used to compare and analyze the EEG signals of people with accommodative dysfunctions and normal controls.The difference is trying to lay the foundation for clinical rapid and objective diagnosis of accommodative dysfunctions.Methods: Collected 10 patients with accommodative dysfunctions in the outpatient of the First Affiliated Hospital of Da Lian Medical University from September 2020 to December 2020,recruited 10 normal people without any visual symptoms as controls,and gave them each personal the flipper stimulation for 1 minute,while using a 32-lead Brain Products electrode cap(eego TMmylab)to record EEG signals.For this 1-minute flipper stimulation experimental data,preprocessing and time-frequency analysis are performed;the middle 2 reversals perform wavelet time-frequency transformation of EEG data in the flipper process(1 time for +2.00 D lens and 1 time for ﹣2.00 D lens);wavelet time-frequency analysis is used to calculate the relative energy of each rhythm(Delta,Theta,Alpha and Beta).To compare and analyze the differences of EEG between individuals with accommodative dysfunctions and the normal.Results: Within 0.5s,there was a significant difference in EEG characteristics between normal people and those with accommodative dysfunctions: Brain topography: During normal people’s visual accommodation,the occipital parietal area and part of the prefrontal area of the brain were obviously activated.In contrast,the patient’s brain topographic map is not active,most of the brain areas are deactivated;time-frequency analysis: the patient is less active than normal people,which is consistent with the analysis of the brain topographic map;changes in the relative energy of each rhythm:The Alpha wave and Beta wave of the EEG of the two groups of experimenters have large peaks when they are adjusted.There is a significant difference in the ratio of the Beta frequency band energy(Beta frequency band energy/total energy of each frequency band)between patients and normal people p=0.005(P <0.01),there is no statistical difference in Alpha,Theta,and Delta frequency bands;behavioral data:normal people have significantly more turnover times than those with accommodative dysfunction,and there is a significant difference in the number of turnover times within1 minute between the two groups of subjects p=0.0404(p<0.05).Conclusion: Within 0.5s,there are obvious differences between the EEG characteristics of normal people and those with accommodative dysfunctions.Normal people’s Beta frequency band energy ratio(Beta frequency band energy/total energy of each frequency band)is higher,and the brain is more active during visual accommodation,and the active position is in the parietal area and the forehead area.The visual adjustment function of normal people is better than those of the abnormal ones.In the process of visual accommodation,the parieto-occipital area and part of the prefrontal area play an important role.Beta rhythm is involved in the accommodation.In the process,the study,through the analysis of EEG,also helps to further study the brain’s visual accommodation mechanism and lays a foundation for the rapid and objective diagnosis of visual accommodation dysfunction.