Randomized Controlled Trial In Individual Patients For Cervical Spondylosis By Qihuang Acupuncture Therapy

ObjectivesTo study the efficacy of the treatment of cervical spondylosis and safety,randomized controlled trial was carried out to figure out treatment efficacy discrepancy between qihuang acupuncture therapy and Indomethacin Cataplasm.MethodsSix patients who met inclusion criteria was allocated randomly to experimental group and control group and then completed the 2-cycle trial,and each cycle consisted of 2 periods.Participants obtained Qihuang acupuncture therapy or Indomethacin Cataplasm randomly at every period.Symptom score and Northwick Park(NPQ)score were used to measure treatment efficacy discrepancy between experimental group and control group before starting and after each period,and a follow-up visit was made 1 week after the whole trial was completed.Results1.Symptom score efficacy comparison:univariate general linear model was used to analyse data of symptom score after trial,based on the characteristic of individual patient trial,and treatment effect indicated that difference was significant between experimental group and controlled group,accurately,mean score of experimental group was lower 1.5 than controlled group.While period effect indicated that there was no significant difference between these two groups.2.Symptom score Meta analysis:six participants were used as six independent studies,and Meta analysis of symptom score showed that the efficacy of Qihuang acupuncture therapy was better than the control group([SMD=-1.38,95%CI[-2.25,-0.51],P=0.002]).3.NPQ score efficacy comparison:univariate general linear model was used to analyse data of NPQ score after trial,based on the characteristic of individual patient trial,and treatment effect indicated that difference was significant between experimental group and control group,accurately,mean score of experimental group was lower 2.16 than control group.Meanwhile,period effect indicated that there was significant difference between these two groups.4.NPQ score Meta analysis:six participants were used as six independent studies,and Meta analysis of NPQ score showed that the efficacy of Qihuang acupuncture therapy was not better than the control group([SMD=-2.22,95%CI[-10.51,7.51],P=0.16]).ConclusionThe efficacy of Qihuang acupuncture therapy for cervical spondylosis is better than Indomethacin Cataplasm,and the Qihuang acupuncture therapy is of great safety.