Clinical Observation Of Qinglin Decoction In The Treatment Of Lower Jiao Damp-heat Acute Cystitis

Purpose:In this study,the clinical efficacy and adverse reactions of Qinglin prescription in the treatment of patients with acute cystitis of lower Jiao damping-heat type were observed by comparing the changes of urine white blood cell count,TCM syndrome accumulation table,urine bacterial culture negative rate and relevant laboratory examination data before and after treatment.Methods:Research object is derived from January 2020-December 2020 fujian university of traditional Chinese medicine affiliated hospital of xiamen nephrology outpatient,in accordance with the requirements of the subject of hardness in syndrome,94 cases of patients with acute cystitis,using the method of random divided into control group and observation group,47 cases were performed in the two groups generally foundation treatment,on the basis of the general treatment,control group and levofloxacin tablets treatment,observation group with clear spray treatment,treatment 3 days,followed up for 7 days.Urine white blood cell count,urine culture results,TCM syndrome scores and other relevant laboratory indicators were collected before and after treatment and follow-up for 7 days.SPSS22.0software was used for statistical analysis and evaluation of the data.Results:1.A total of 94 patients were included in this study,including 91 patients who completed this study.One patient in the control group voluntarily stopped taking drugs during treatment,one patient took other antibiotics during treatment,and one patient in the observation group refused this experiment due to personal reasons,with a shedding rate of3.19% and all of them were treated as invalid.Before treatment,there was no statistical significance in age,body weight,urine white blood cell count,laboratory indicators and TCM syndrome scores between the two groups(P > 0.05),indicating comparability.2.The total effective rate of the control group was 86.67%,and the total effective rate of the observation group was 86.96%,with no significant difference(P > 0.05).There were significant differences in urine white blood cell count and TCM syndrome score between 2groups before and after treatment(P < 0.05).There was no significant difference in urine white blood cell count and TCM syndrome score between 2 groups after treatment(P >0.05).Comparison of single TCM symptoms between the two groups after treatment showed statistically significant difference except for frequency and urgency of urine(P < 0.05),while no significant difference was found in other TCM symptoms(P > 0.05).There was no significant difference in urine bacterial culture conversion rate between the two groups after treatment(P > 0.05).3.The recurrence rate of patients in the two groups after 7 days of follow-up was compared and analyzed,the recurrence rate in the control group was 20.51%,and the recurrence rate in the observation group was 2.50%,with statistical significance(P < 0.05).4.The incidence of adverse reactions in patients in the two groups was compared and analyzed.The incidence of adverse reactions in the control group was 13.33%,while there was no adverse reaction in the observation group,with statistical significance(P < 0.05).5.In the process of clinical observation,the blood routine,liver and kidney function,electrolyte and other laboratory indexes of all patients before and after treatment were compared,and the results were not significant by statistical analysis(P > 0.05).Conclusion:1.Qinglin prescription alone can significantly reduce the urine white blood cell count and TCM syndrome score of patients with acute cystitis of lower coke damp-heat type,and improve the clinical symptoms.2.The recurrence rate of acute cystitis treated by Qinglin prescription alone was significantly lower than that treated by levofloxacin alone.3.The incidence of adverse reactions of Qinglin prescription alone in the treatment of acute cystitis of lower coke damp-heat type was significantly lower than that of levofloxacin tablet alone.