Clinical Observation Of Shenyan Zhixue Decoction On Isolated Hematuria After Henoch Schonlein Purpura Of Hyperactivity Of Fire Due To Yin Deficiency Type In Children

Objective:This topic through the observation of Shenyan Zhixue decoction on the treatment of children with isolated hematuria after Henoch Schonlein purpura of Hyperactivity of fire due to yin deficiency type and urine sediment changes in the number of red blood cells,which was intended to analyze the probability and security of its efficacy.Methods:34 patients diagnosed with isolated hematuria after Henoch Schonlein purpura of Hyperactivity of fire due to yin deficiency type by the clinic of the First Affiliated Hospital,Heilongjiang University of Chinese Medicine and Department of Nephrology,Harbin Children’s Hospital from 12,2019 to 12,2020 were selected as the study subjects,and these 34 patients were randomly divided into two groups.The test group took Shenyan Zhixue decoction orally,while the control group took Hematuresis capsule and Zhibai Dihuang pill orally.Both groups were treated for three months as a course.The clinical effects were observed 2 weeks,1 month,2 months and 3 months after taking medicine.Results:1.At the end of the treatment,16 patients in the experimental group and 15 patients in the control group met the requirements and achieved the expected goal.2.Analysis of the total efficacy:After 2 weeks,1 month,2 months and 3 months of treatment,the total effective rate of the experimental group(70.6%、76.5%、82.4%、87.5%)was significantly higher than that of the control group(P<0.05).3.Comparison of TCM syndrome score:After treatment,the total effective rate was 87.5%in the experimental group and 73.3%in the control group,the difference was statistically significant(P<0.05).Among them,the improvement of dizziness symptom was the most significant than the control group(P<0.01);in the improvement of irritability symptoms,there are statistical differences(P<0.05);but for thirst,feverish feeling in palms and soles,night sweats,it was not significant(P>0.05).4.Recurrence rate comparison:After 3 months of follow-up,the recurrence rate was 7.14%in the experimental group and 18.18%in the control group.There was no significant difference between the two groups(P<0.05).Conclusion:1.Shenyan Zhixue decoction has significant clinical effect in the treatment of isolated hematuria after Henoch Schonlein purpura of hyperactivity of fire due to yin deficiency type.2.Shenyan Zhixue decoction can effectively improve the symptoms of thirst,dizziness,night sweat,irritability,feverish feeling in palms and soles in children with isolated hematuria after purpura,especially for dizziness and irritability.3.Shenyan Zhixue decoction can significantly reduce the urine sediment red blood cell count of children with isolated hematuria after Henoch Schonlein purpura of hyperactivity of fire due to yin deficiency type.