Summary Of Professor Xie Jingri’s Clinical Experience In The Treatment Of Peptic Ulcer

Objective:To summarize the characteristics,regularity and clinical experience of Professor Xie Jingri in the treatment of peptic ulcer through the retrospective analysis of Professor Xie Jingri’s previous clinical cases in the treatment of peptic ulcer.Methods:Collect the clinical records of Professor Xie Jingri in the treatment of peptic ulcer from January 2015 to January 2020,screen the first medical records of 153 peptic ulcer patients who meet the research standards,and integrate the data.the database of peptic ulcer prescription was established by using the Traditional Chinese Medicine Inheritance Support System(V2.5),and the data analysis results were obtained by using the two modules of "statistical report" and "data analysis" in the platform.Results:Using the Traditional Chinese Medicine Inheritance Support System(V2.5),153 cases of peptic ulcer treated by Professor Xie Jingri were statistically analyzed,with 153 prescriptions for the first diagnosis.The results of data mining are as follows:1.Among the 153 medical records in this study,there are more males than females,and the age group is mainly concentrated in 50-59 years old and 40-49 years old,accounting for 53.60% of the total population,followed by 60-69 years old group,accounting for about 18.30% of the total population.2.In this study,the syndrome classification of peptic ulcer from high to low is spleen-stomach weakness syndrome,liver-stomach disharmony syndrome,spleen-stomach damp-heat syndrome,liver-stomach stagnationheat syndrome,stomach yin deficiency syndrome,stomach collateral stasis syndrome.3.In the prescription of this study,a total of 126 traditional Chinese medicines were used,and the total frequency of all drugs was 2941.The top15 flavors most frequently used were Bupleurum,Atractylodes macrocephala,cuttlebone,perilla,white cardamom,bergamot,Shenqu,tangerine peel,black medicine,calcined corrugated seed,magnolia,astragalus,cardamom,Amomum,chicken inner gold.4.In this study,the top 9 drug categories were qi-regulating drugs,deficiency-tonifying drugs,dampness-relieving drugs,phlegm-relieving cough and asthma-relieving drugs,antipyretic drugs,surface-relieving drugs,blood-activating and stasis-activating drugs and astringent drugs,accounting for 85.72% of the total frequency.5.In the statistics of drug meridian,the four qi are mainly warm,cold and flat,the five flavors are mainly pungent,bitter and sweet,and the meridians are mainly spleen meridian,stomach meridian,lung meridian and liver meridian.6.In this study,Professor Xie Jingri’s common drug combination in the treatment of peptic ulcer was 248 groups,including 39 groups of 2commonly used drugs,37 groups of 3 drugs and 9 groups of 4 drugs.7.In this study,14 potential core combinations and 7 potential new combinations were extracted.Conclusion:1.Professor Xie Jingri advocated that peptic ulcer should take weakness of spleen and stomach,imbalance of liver and spleen and loss of stomach collaterals as the basic pathogenesis,start with liver and spleen,and pay attention to regulating the whole body qi and protecting gastrointestinal mucosa.2.Professor Xie Jingri treats peptic ulcer by soothing the liver,regulating qi and invigorating the spleen,inhibiting acid and stomach as the basic treatment,combined with clearing heat and resolving dampness and stomach,promoting blood circulation and removing blood stasis and relieving pain to treat patients with peptic ulcer based on syndrome differentiation.3.Professor Xie Jingri’s drugs for treating peptic ulcer are pungent,bitter,sweet,warm,cold and flat,and mainly belong to spleen,stomach,lung and liver meridian;commonly used drugs are Bupleurum,bergamot,Atractylodes macrocephala,Radix Astragali,Cuttlebone,calcined corrugated seed,Perilla seed,Amomum,Magnolia,White Cardamom,Black Medicine,Cardamom,Shenqu,tangerine Peel,Chicken Gold and so on.