COX Analysis And Summary Of Traditional Chinese Medicine Treatment In 55 Patients With Small Cell Lung Cancer

Objective: To explore whether TCM syndrome differentiation is an independent prognostic factor affecting the survival of patients with small cell lung cancer,and to summarize the medication rules of traditional Chinese medicine decoction,so as to provide reference for clinical practice.Materials and methods: from September 2017 to September 2020,patients with small cell lung cancer who were hospitalized in the oncology department of the Affiliated Hospital of Liaoning University of traditional Chinese medicine were selected,and their basic information,physical status score,clinical stage,serological test index,TCM syndrome differentiation,survival period,and the use of traditional Chinese medicine were entered into Microsoft In order to find out the independent prognostic factors that affect the survival of patients,univariate and multivariate analysis were performed.At the same time,the use of traditional Chinese medicine was summarized and analyzed.All the above data were processed by spss26.0 statistical software,P<0.05 showed statistical significance.Result:1.The median survival time of 55 patients with small cell lung cancer was 16 months.2.Multivariate analysis of prognosis of patients with small cell lung cancer showed that clinical stage,radiotherapy and chemotherapy,lactate dehydrogenase and syndrome differentiation were independent prognostic factors for survival of patients with small cell lung cancer.3.55 cases of small cell lung cancer were divided into four syndrome types: lung spleen deficiency,Qi and yin deficiency,heat toxin obstructing lung,phlegm dampness and blood stasis.4.55 cases of small cell lung cancer patients in TCM syndrome differentiation,the median survival time from long to short were: lung and spleen deficiency syndrome,Qi and yin deficiency syndrome,heat toxin obstructing lung syndrome,phlegm dampness and blood stasis syndrome,in which lung and spleen deficiency syndrome,Qi and yin deficiency syndrome,heat toxin obstructing lung syndrome patients' survival time was significantly longer than phlegm dampness and blood stasis syndrome,P<0.05,with statistical significance.Conclusion:1.Clinical stage,radiotherapy and chemotherapy,lactate dehydrogenase and syndrome differentiation are independent prognostic factors for survival of patients with small cell lung cancer.2.In this study,the prognosis of small cell lung cancer with phlegm dampness and blood stasis is the worst.3.Oral decoction can affect the prognosis of patients with small cell lung cancer,relieve symptoms and improve the survival time of patients.The use of traditional Chinese medicine prescriptions is related to TCM syndrome types.Most of the traditional Chinese medicine decoction pieces used by patients with small cell lung cancer have the effects of moistening lung and spleen,clearing heat and purging fire,cooling blood and detoxifying,supplementing qi and nourishing Yin,resolving phlegm,relieving cough and asthma,etc.,reflecting the TCM thought of syndrome differentiation and treatment and holistic concept.