Effect Of Traditional Chinese Medicine Ba Duan Jin On Intervention Of Patients With Non - Small Cell Lung Cancer

this s consists of two parts:literature review and the clinical observation.Literature review is also made up of western medicine part and traditional Chinese medicine part:literature review of western medicine will discusses relative information of surgical treatment of non-small cell lung cancer (NSCLC), post-operative complications and rehabilitation methods of post-operative, etc. The TCM part will discusses the recognition of etiology and pathogenesis of lung cancer in TCM and also the treatment and differentiation. Meanwhile the mechanism and clinical effects of Baduanjin exercise will be discussed from many aspects like theory of TCM and clinical practice. Applying the Baduanjin to the rehabilitation of post-operative NSCLC patients tactfully, for the goal of treating modern disease by ancient method., to provide a new idea for post-operative NSCLC patients’rehabilitation therapy.The clinical observation is about observing the clinical safeties and therapeutic effects of traditional Chinese medicine rehabilitation sport Baduanjin.Purpose:observing the therapeutic effects of traditional Chinese medicine rehabilitation sport Baduanjin, and respiratory function,6MWD, etc. and also the clinical safeties of Baduanjin.Object:choosing 61 post-operative patients diagnosed with NSCLC by pathology.DOE(Design of experiments):The test is a prospective, controlled clinical study. Through the CHISS software generating random numbers table, divide 61 patients into two groups randomly:one is the treatment group including 31 patients and another is the control group with 30 patients.before the beginning of treatment, the normal information of patients like:name, sexuality, age, contact number, diagnosis, Past Medical History, vital signs, physical examination, will be recorded, also does the 6MWD, FVC, FEV1, FEV1/FVC, FACT-L4.0, fatigue(BFI score), dyspnea(VAS score), pain(NRS score) etc. Patients of sport group will receive group exercise and individual exercise of Baduanjin. We require patients to learn standardized Baduanjin from professional sport teacher provided by us for the first week,3 times a week, one time 1 h, and then practise Baduanjin with the vedio,5 days a week, twice a day,30 min for each time. People can add personal sports appropriately (aerobics mainly for warming up or relaxing), free style and can not beyond 15min. We also ask patients to maintain their rating of perceived exertion or corresponding heart rate during the exercise. Patients of control group will not take any rehabilitation intervention. After 3 months, we exam data according to those inspection items took before the intervention, and compare the two groups of data. Evaluating the safety of Baduanjin by comparing the blood examination and biochemical tests of liver, kidney function.Results:Into the group of 61 cases of patients, falling off 1 cases, finishing the clinical observation with the rest 60 patients, the KPS score of two group >80, meanwhile, the sexuality, age, ECOG score, KPS score, lung cancer staging, 6MWD, FVC, FEV1, FEV1/FVC, FACT-L4.0 score, fatigue(BFI score), dyspnea (VAS score), pain (NRS score) and clinical symptom, etc, had no statistical difference. After 3 months’ treatment, compare the two groups, the respiratory function index:FEV1 and FVC,6MWD, physiological condition, emotional and functional condition, fatigue condition were all changed with statistical significance(P < 0.05). Meanwhile, by comparison blood examination and biochemical tests of liver, kidney function between prior treatment and after treatment, no abnormality and treatment relative side-effects had been found.Conclusion:1. Respiratory function and airway obstruction condition could be improved through 3-month Baduanjin exercise.2. Cardio-pulmonary function and exercise tolerance could be enhanced by 3-month Baduanjin exercise.3. Baduanjin exercise is beneficial for improvement of patients’mental and physical condition. However the social/fami ly condition and add it ional concerning condition of FACT-L 4.0 had shown no improvement.4. The difference of fatigue level between two groups had been shown after treatment, moreover, the improvement of treatment group is better than control group, there is no evidence can prove Baduanjin’s therapeutic effect for pain and dyspnea.5. The safety of Baduanjin exercise is benign.