Study On The Medication Regularity Of Professor Zhou Yabin In The Treatment Of Female Insomnia

Objective: Through data mining and analysis of Professor Zhou Yabin’s medication characteristics and prescription rules in the treatment of female insomnia,Professor Zhou’s experience in treating female insomnia was summarized,in order to provide new ideas for clinical diagnosis and treatment of female insomnia.Methods: In this study,the prescriptions of female insomnia patients who visited Professor Zhou Yabin’s clinic from September 2018 to December2020 were collected and analyzed using softwares such as traditional Chinese medicine inheritance computing platform V3.0 and Excel to obtain the age distribution of patients,the frequencies of prescription drugs,the characteristics of Professor Zhou’s medication in the treatment of this disease were summarized in terms of properties and flavors,function categories,drug association rules,core prescriptions,symptoms,and tongue and pulse.Results:1.A total of 174 traditional Chinese medicines in 356 prescriptions were analyzed,and the results showed that Professor Zhou used plenty of tonics and tranquilizers when treating female insomnia,and the frequency was 1435 times and 1074 times respectively.The frequencies of the four qi of the drug were: cold(2623 times),flat(2015 times),warm(1804 times),cool(283 times),and hot(55 times).The frequencies of the five flavors of the drug were: sweet(3790 times),bitter(2970 times),pungent(2432times),sour(1129 times),and salty(748 times).The main meridians of the medicines were the Lung Meridian(3618 times),the Spleen Meridian(3354times),the Heart Meridian(3220 times),the Liver Meridian(3049 times)and the Stomach Meridian(1983 times).2.The results of frequency analysis of 174 traditional Chinese medicines showed that the 20 drugs with the highest frequency were Licorice,Pinellia Ternata,Radix Bupleuri,Scutellaria baicalensis,Radix Paeoniae Alba,Os Draconis,Oyster,Cassia Twig,Polygala,Rhubarb,Semen Ziziphi Spinosae,Fushen,Lilium Brownii,Rhizoma Nardostachyos,Floating Wheat,Polygni Multiflori Caulis,Cyperi Rhizoma,Astragali Radix,Codonopsis Pilosula,Platycodon grandiflorum.The core prescription is composed of Radix Bupleuri,Cassia Twig,Radix Paeoniae Alba,Pinellia Ternata,Scutellaria baicalensis,Os Draconis,Oyster and Licorice.High frequency drug combination were: Radix Bupleuri-Radix Paeoniae Alba,Os Draconis-Oyster,Semen Ziziphi Spinosae-Fushen-Polygala and so on.Four drug cluster combinations were obtained by cluster analysis.Conclusions:1.The distribution of female insomnia patients in this study increased with age.2.Professor Zhou Yabin’s treatment of female insomnia is based on the basic principles of adjusting yin and yang,tonifying deficiency and reducing excess.For female insomnia patients with liver depression and qi stagnation,heart and spleen deficiency,Professor Zhou often uses Chaihu Jia Longgu Muli Decoction and Guipi Decoction.